Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.300 limited 1.000 12 0 2003 2017
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B 		P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.300 limited 1.000 8 0 1998 2015
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.300 limited 1.000 7 0 2013 2018
Entrez Id: 27030
Gene Symbol: MLH3
MLH3 		Q9UHC1 mutL homolog 3 Nucleic acid binding 108 0.582 0.538 4.9E-08 0.500 moderate 1.000 7 0 2003 2009
Entrez Id: 9156
Gene Symbol: EXO1
EXO1 		Q9UQ84 exonuclease 1 Enzyme 87 0.578 0.692 8.1E-13 0.310 disputed 1.000 6 0 2000 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.300 limited 1.000 6 0 1998 2016
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.300 moderate 1.000 6 0 2012 2017
Entrez Id: 4437
Gene Symbol: MSH3
MSH3 		P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.300 limited 1.000 6 0 1996 2016
Entrez Id: 22909
Gene Symbol: FAN1
FAN1 		Q9Y2M0 FANCD2 and FANCI associated nuclease 1 93 0.610 0.577 1.7E-25 0.300 limited 1.000 4 0 2010 2016
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.300 limited 1.000 4 0 2001 2016
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.320 None 1.000 3 0 1998 2004
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.300 limited 1.000 3 0 1994 2015
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4 		P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.300 limited 1.000 2 0 2015 2016
Entrez Id: 64218
Gene Symbol: SEMA4A
SEMA4A 		Q9H3S1 semaphorin 4A Signaling 141 0.569 0.692 1.8E-05 0.300 limited 1.000 2 0 2014 2016
Entrez Id: 6224
Gene Symbol: RPS20
RPS20 		P60866 ribosomal protein S20 Nucleic acid binding 86 0.610 0.692 2.1E-02 0.300 limited 1.000 2 0 2014 2017
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ 		Q12913 protein tyrosine phosphatase receptor type J Enzyme 79 0.606 0.615 1.3E-11 0.300 limited 1.000 1 0 2017 2017
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 1 0 1995 1995
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6790
Gene Symbol: AURKA
AURKA 		O14965 aurora kinase A Kinase 245 0.475 0.731 0.87 0.010 None 1.000 1 0 2007 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2007 2007
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4 		Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.300 limited 1.000 1 0 2015 2015
Entrez Id: 768
Gene Symbol: CA9
CA9 		Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.010 None 1.000 1 0 2007 2007
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.010 None 1.000 1 0 2007 2007
Entrez Id: 960
Gene Symbol: CD44
CD44 		P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.300 None 1.000 1 0 2017 2017