Source: ALL
Gene | UniProt | Gene Full Name | Protein Class | N. diseases g | DSI g | DPI g | pLI | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Q86YC2 | partner and localizer of BRCA2 | 260 | 0.485 | 0.769 | 3.0E-19 | 0.300 | limited | 1.000 | 7 | 0 | 2013 | 2018 | |||||
|
P07099 | epoxide hydrolase 1 | 196 | 0.500 | 0.846 | 3.2E-09 | 0.300 | limited | 1.000 | 3 | 0 | 1994 | 2015 | |||||
|
P35749 | myosin heavy chain 11 | 161 | 0.528 | 0.731 | 0.77 | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | |||||
|
Q13426 | X-ray repair cross complementing 4 | 192 | 0.528 | 0.769 | 8.3E-07 | 0.300 | limited | 1.000 | 1 | 0 | 2015 | 2015 | |||||
|
Q9H3S1 | semaphorin 4A | Signaling | 141 | 0.569 | 0.692 | 1.8E-05 | 0.300 | limited | 1.000 | 2 | 0 | 2014 | 2016 | ||||
|
Q9UQ84 | exonuclease 1 | Enzyme | 87 | 0.578 | 0.692 | 8.1E-13 | 0.310 | disputed | 1.000 | 6 | 0 | 2000 | 2014 | ||||
|
Q05823 | ribonuclease L | Kinase | 85 | 0.579 | 0.692 | 2.0E-10 | 0.010 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||
|
Q9UHC1 | mutL homolog 3 | Nucleic acid binding | 108 | 0.582 | 0.538 | 4.9E-08 | 0.500 | moderate | 1.000 | 7 | 0 | 2003 | 2009 | ||||
|
P35221 | catenin alpha 1 | Cellular structure | 82 | 0.584 | 0.538 | 0.97 | 0.300 | 0 | 0 | ||||||||
|
Q99728 | BRCA1 associated RING domain 1 | 75 | 0.597 | 0.538 | 1.4E-24 | 0.300 | limited | 1.000 | 4 | 0 | 2001 | 2016 | |||||
|
Q86XK2 | F-box protein 11 | Enzyme | 93 | 0.604 | 0.692 | 1.00 | 0.100 | None | 1.000 | 125 | 273 | 1991 | 2017 | ||||
|
Q12913 | protein tyrosine phosphatase receptor type J | Enzyme | 79 | 0.606 | 0.615 | 1.3E-11 | 0.300 | limited | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
Q9Y2M0 | FANCD2 and FANCI associated nuclease 1 | 93 | 0.610 | 0.577 | 1.7E-25 | 0.300 | limited | 1.000 | 4 | 0 | 2010 | 2016 | |||||
|
P60866 | ribosomal protein S20 | Nucleic acid binding | 86 | 0.610 | 0.692 | 2.1E-02 | 0.300 | limited | 1.000 | 2 | 0 | 2014 | 2017 | ||||
|
Q9BYH8 | NFKB inhibitor zeta | 30 | 0.674 | 0.577 | 1.00 | 0.300 | limited | 1.000 | 1 | 0 | 2015 | 2015 |