Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.010 None 1.000 1 0 2004 2004
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.040 None 1.000 4 0 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.020 None 0.500 2 0 2014 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.700 None 1.000 16 4 2004 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.010 None 1.000 1 0 2018 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.600 None 1.000 14 2 2014 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 994 0.321 0.962 0.61 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.010 None 1.000 1 0 1994 1994
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 957 0.325 0.923 0.99 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.010 None 1.000 1 0 2014 2014
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.010 None 1.000 1 0 2001 2001
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 665 0.356 0.846 1.2E-04 0.030 None 1.000 3 0 2010 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 681 0.362 0.923 1.8E-02 0.010 None 1.000 1 0 2014 2014
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 553 0.362 0.769 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 705 0.363 0.846 0.010 None 1.000 1 0 2010 2010
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 652 0.373 0.923 3.0E-02 0.080 None 0.875 8 0 2018 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 561 0.378 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12 		P48061 C-X-C motif chemokine ligand 12 593 0.379 0.846 0.12 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 339 0.398 0.885 1.00 0.010 None 1.000 1 0 2006 2006
Entrez Id: 6121
Gene Symbol: RPE65
RPE65 		Q16518 retinoid isomerohydrolase RPE65 Enzyme 379 0.417 0.808 6.5E-14 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		O14733 mitogen-activated protein kinase kinase 7 Kinase 394 0.419 0.808 1.00 0.020 None 1.000 2 0 2016 2018
Entrez Id: 6662
Gene Symbol: SOX9
SOX9 		P48436 SRY-box transcription factor 9 334 0.419 0.846 1.00 0.010 None 1.000 1 0 2017 2017