Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 1.000 None 0.979 2327 632 1989 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.962 80 3 1992 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.970 33 0 1993 2019
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 346 0.447 0.846 1.2E-03 0.100 None 0.962 26 0 1992 2019
Entrez Id: 54498
Gene Symbol: SMOX
SMOX 		Q9NWM0 spermine oxidase 91 0.603 0.769 0.40 0.100 None 0.880 25 0 1990 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.200 None 0.957 23 1 1991 2019
Entrez Id: 4153
Gene Symbol: MBL2
MBL2 		P11226 mannose binding lectin 2 Receptor 563 0.390 0.846 2.7E-03 0.200 None 0.913 23 2 1999 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 18 0 1986 1990
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 18 2 1996 2019
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B 		P51168 sodium channel epithelial 1 subunit beta Ion channel 86 0.628 0.577 5.8E-08 0.600 None 1.000 17 0 2005 2019
Entrez Id: 54738
Gene Symbol: FEV
FEV 		Q99581 FEV transcription factor, ETS family member Transcription factor 86 0.593 0.692 8.1E-03 0.100 None 0.875 16 0 2000 2018
Entrez Id: 55107
Gene Symbol: ANO1
ANO1 		Q5XXA6 anoctamin 1 Ion channel 175 0.516 0.769 0.87 0.100 None 1.000 15 0 2011 2020
Entrez Id: 1773
Gene Symbol: DNASE1
DNASE1 		P24855 deoxyribonuclease 1 180 0.505 0.846 7.0E-21 0.100 None 0.929 14 0 1990 2019
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		Q9HC84 mucin 5B, oligomeric mucus/gel-forming 141 0.532 0.808 1.00 0.100 None 1.000 12 0 1998 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC 		P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.100 None 1.000 11 0 1998 2019
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6 		Q92581 solute carrier family 9 member A6 Transporter 210 0.516 0.846 1.00 0.100 None 1.000 11 0 2009 2020
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A 		P37088 sodium channel epithelial 1 subunit alpha Ion channel 98 0.601 0.577 1.1E-11 0.390 None 0.909 11 1 2004 2017
Entrez Id: 115019
Gene Symbol: SLC26A9
SLC26A9 		Q7LBE3 solute carrier family 26 member 9 Transporter 19 0.743 0.423 1.3E-02 0.100 None 1.000 11 1 2013 2020
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.100 None 1.000 11 0 1996 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.100 None 0.909 11 0 1998 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 1.000 11 0 2007 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 11 0 2000 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 1.000 10 0 1999 2019
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 400 0.431 0.885 8.6E-19 0.100 None 1.000 10 0 2001 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 1.000 10 0 1992 2008