Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 54498
Gene Symbol: SMOX
SMOX
Q9NWM0 spermine oxidase 91 0.603 0.769 0.40 0.100 None 0.880 25 0 1990 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 18 2 1996 2019
Entrez Id: 1773
Gene Symbol: DNASE1
DNASE1
P24855 deoxyribonuclease 1 180 0.505 0.846 7.0E-21 0.100 None 0.929 14 0 1990 2019
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
Q9HC84 mucin 5B, oligomeric mucus/gel-forming 141 0.532 0.808 1.00 0.100 None 1.000 12 0 1998 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 1.000 11 0 2007 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 11 0 2000 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.100 None 0.909 11 0 1998 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 1.000 10 0 1999 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.090 None 1.000 9 0 1996 2019
Entrez Id: 450095
Gene Symbol: PLF
PLF
Pulmonary function 124 0.544 0.731 0.090 None 1.000 9 0 2002 2020
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
P00995 serine peptidase inhibitor Kazal type 1 216 0.492 0.808 0.31 0.090 None 1.000 9 0 1990 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.090 None 1.000 9 1 2005 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.080 None 1.000 8 1 1996 2014
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.080 None 1.000 8 0 2007 2018
Entrez Id: 51297
Gene Symbol: BPIFA1
BPIFA1
Q9NP55 BPI fold containing family A member 1 67 0.617 0.577 1.2E-08 0.080 None 0.875 8 0 2007 2019
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.070 None 1.000 7 0 1993 2016
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
P29475 nitric oxide synthase 1 521 0.408 0.885 1.00 0.070 None 0.714 7 0 2000 2010
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.070 None 1.000 7 0 2004 2019
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
P60022 defensin beta 1 177 0.509 0.808 0.41 0.060 None 1.000 6 0 1997 2011
Entrez Id: 17
Gene Symbol: AAVS1
AAVS1
adeno-associated virus integration site 1 78 0.595 0.731 0.060 None 0.833 6 0 1993 2017
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.160 None 1.000 6 2 1998 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.060 None 1.000 6 0 2010 2019
Entrez Id: 4060
Gene Symbol: LUM
LUM
P51884 lumican 123 0.543 0.731 7.7E-02 0.060 None 1.000 6 0 2017 2019
Entrez Id: 671
Gene Symbol: BPI
BPI
P17213 bactericidal permeability increasing protein 83 0.610 0.769 1.7E-14 0.060 None 1.000 6 0 1998 2019
Entrez Id: 1056
Gene Symbol: CEL
CEL
P19835 carboxyl ester lipase 172 0.514 0.808 1.5E-06 0.050 None 1.000 5 0 2010 2019