Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1773
Gene Symbol: DNASE1
DNASE1 		P24855 deoxyribonuclease 1 161 0.505 0.846 7.0E-21 0.100 None 0.929 14 0 1990 2019
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		Q9HC84 mucin 5B, oligomeric mucus/gel-forming 114 0.532 0.808 1.00 0.100 None 1.000 12 0 1998 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC 		P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 210 0.483 0.808 1.0E-08 0.100 None 1.000 11 0 1998 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 1.000 11 0 2007 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 1.000 11 0 2000 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 584 0.377 0.923 7.1E-15 0.100 None 1.000 11 0 1996 2019
Entrez Id: 115019
Gene Symbol: SLC26A9
SLC26A9 		Q7LBE3 solute carrier family 26 member 9 Transporter 17 0.743 0.423 1.3E-02 0.100 None 1.000 11 1 2013 2020
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 572 0.364 0.923 4.0E-15 0.100 None 0.909 11 0 1998 2019
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6 		Q92581 solute carrier family 9 member A6 Transporter 134 0.516 0.846 1.00 0.100 None 1.000 11 0 2009 2020
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 361 0.431 0.885 8.6E-19 0.100 None 1.000 10 0 2001 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 839 0.344 0.885 1.3E-05 0.100 None 1.000 10 0 1992 2008
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.100 None 1.000 9 0 1999 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.090 None 1.000 9 1 2005 2019
Entrez Id: 450095
Gene Symbol: PLF
PLF 		Pulmonary function 124 0.544 0.731 0.090 None 1.000 9 0 2002 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 932 0.333 0.962 1.6E-04 0.090 None 1.000 9 0 1996 2019
Entrez Id: 166
Gene Symbol: TLE5
TLE5 		Q08117 TLE family member 5, transcriptional modulator Transcription factor 31 0.695 0.538 0.94 0.090 None 1.000 9 0 2007 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.090 None 1.000 8 0 2007 2020
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		P07550 adrenoceptor beta 2 G-protein coupled receptor 323 0.442 0.923 0.53 0.090 None 1.000 8 2 2002 2018
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1 		P00995 serine peptidase inhibitor Kazal type 1 179 0.492 0.808 0.31 0.090 None 1.000 7 0 1990 2016
Entrez Id: 51297
Gene Symbol: BPIFA1
BPIFA1 		Q9NP55 BPI fold containing family A member 1 60 0.617 0.577 1.2E-08 0.080 None 0.875 8 0 2007 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.080 None 1.000 8 1 1996 2014
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.080 None 1.000 7 0 2007 2018
Entrez Id: 353
Gene Symbol: APRT
APRT 		P07741 adenine phosphoribosyltransferase 370 0.423 0.846 5.5E-13 0.070 None 1.000 7 0 1993 2016
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.070 None 1.000 7 0 1985 2018
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		P29475 nitric oxide synthase 1 399 0.408 0.885 1.00 0.070 None 0.714 7 0 2000 2010