Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 284 0.479 0.808 1.00 0.400 None 1.000 13 3 2009 2020
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.100 None 1.000 11 3 2012 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 0.900 10 3 2015 2020
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 225 0.510 0.846 1.00 0.380 None 0.800 8 3 2010 2019
Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
Q96EV8 dystrobrevin binding protein 1 93 0.588 0.615 6.8E-06 0.330 None 1.000 4 3 2008 2013
Entrez Id: 8863
Gene Symbol: PER3
PER3
P56645 period circadian regulator 3 Transcription factor 122 0.559 0.731 1.4E-17 0.430 None 1.000 4 3 2009 2018
Entrez Id: 8914
Gene Symbol: TIMELESS
TIMELESS
Q9UNS1 timeless circadian regulator 140 0.533 0.808 9.8E-35 0.320 None 1.000 2 3 2009 2010
Entrez Id: 9248
Gene Symbol: GPR50
GPR50
Q13585 G protein-coupled receptor 50 G-protein coupled receptor 31 0.686 0.462 0.65 0.020 None 1.000 2 3 2009 2015
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.010 None 1.000 1 3 2017 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.110 None 1.000 1 3 2016 2016
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 287 0.469 0.846 0.84 0.400 None 1.000 13 2 2001 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.400 None 1.000 12 2 1996 2020
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.570 None 1.000 11 2 2007 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.360 None 1.000 10 2 2012 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.090 None 1.000 9 2 2012 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.350 None 0.500 6 2 2003 2019
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 248 0.492 0.808 8.5E-05 0.340 None 1.000 5 2 2008 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.050 None 1.000 5 2 2011 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.040 None 1.000 4 2 2017 2019
Entrez Id: 6095
Gene Symbol: RORA
RORA
P35398 RAR related orphan receptor A Nuclear receptor 158 0.533 0.808 0.40 0.340 None 1.000 4 2 2010 2017
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.320 None 1.000 3 2 2011 2016
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.130 None 1.000 3 2 2018 2019
Entrez Id: 22953
Gene Symbol: P2RX2
P2RX2
Q9UBL9 purinergic receptor P2X 2 Ion channel 99 0.585 0.769 9.7E-13 0.010 None 1.000 1 2 2013 2013
Entrez Id: 2638
Gene Symbol: GC
GC
P02774 GC vitamin D binding protein Transporter 219 0.489 0.885 2.7E-11 0.010 None < 0.001 1 2 2018 2018
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.100 None 0 2