Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.300 None 1.000 1 0 2011 2011
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.200 None 1.000 1 0 1998 1998
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.200 None 1.000 1 0 2006 2006
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.200 None 1.000 1 0 2017 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.200 None 1.000 4 0 2006 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.200 None 1.000 1 0 2008 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.200 None 1.000 1 0 2014 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.500 None 1.000 3 0 2009 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.500 None 1.000 3 0 2008 2017
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.200 None 1.000 1 0 2005 2005
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.300 None 1.000 1 0 2004 2004
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.200 None 1.000 1 0 2006 2006
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.200 None 1.000 1 0 2013 2013
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.500 None 1.000 4 0 2003 2011
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.500 None 1.000 4 0 2002 2010
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.200 None 1.000 1 0 2013 2013
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.500 None 1.000 5 0 2004 2013
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.500 None 1.000 3 0 2006 2012
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.200 None 1.000 2 0 2012 2012
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.300 None 1.000 3 0 2005 2008
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.200 None 1.000 2 0 2011 2013