Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.500 None 1.000 3 0 2009 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.300 None 1.000 3 0 2005 2008
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.500 None 1.000 3 0 2011 2013
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.500 None 1.000 3 0 2009 2013
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
P04839 cytochrome b-245 beta chain Ion channel 343 0.452 0.885 1.00 0.500 None 1.000 3 0 2001 2009
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.200 None 1.000 3 0 2005 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.500 None 1.000 3 0 2008 2017
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 Transporter 235 0.493 0.808 1.5E-10 0.500 None 1.000 3 0 2004 2009
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 345 0.459 0.846 1.00 0.200 None 1.000 3 0 2008 2012
Entrez Id: 2936
Gene Symbol: GSR
GSR
P00390 glutathione-disulfide reductase Enzyme 206 0.494 0.846 1.3E-06 0.500 None 1.000 3 0 2010 2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.500 None 1.000 3 0 2002 2012
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
P17302 gap junction protein alpha 1 Cell-cell junction 662 0.393 0.885 0.16 0.200 None 1.000 3 0 2010 2012
Entrez Id: 590
Gene Symbol: BCHE
BCHE
P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.200 None 1.000 3 0 2001 2005
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 159 0.518 0.808 1.5E-02 0.500 None 1.000 3 0 2000 2013
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 233 0.488 0.769 2.4E-02 0.500 None 1.000 3 0 2012 2013
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.300 None 1.000 3 0 2003 2013
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
P11413 glucose-6-phosphate dehydrogenase Enzyme 410 0.424 0.846 0.97 0.200 None 1.000 3 0 2006 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.500 None 1.000 3 0 2005 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.500 None 1.000 3 0 2005 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 1.000 3 0 2011 2015
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 483 0.406 0.885 1.00 0.500 None 1.000 3 0 2008 2012
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
P30542 adenosine A1 receptor G-protein coupled receptor 121 0.578 0.692 1.5E-02 0.200 None 1.000 3 0 1998 2006
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.200 None 1.000 3 0 1992 2009
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
Q16853 amine oxidase copper containing 3 106 0.561 0.769 6.3E-11 0.500 None 1.000 3 0 1990 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.500 None 1.000 3 0 2006 2012