Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.400 None 0.990 581 2 1986 2020
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2
P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.100 None 0.977 488 3 2005 2020
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.100 None 0.979 487 2 2005 2020
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.500 None 0.978 449 6 1993 2020
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 257 0.485 0.846 1.00 0.700 None 0.965 402 34 2006 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.600 None 0.950 342 23 1999 2020
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1
Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 371 0.460 0.808 1.00 0.100 None 0.970 298 3 1993 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.700 None 0.953 279 20 1998 2020
Entrez Id: 3375
Gene Symbol: IAPP
IAPP
P10997 islet amyloid polypeptide Signaling 183 0.507 0.808 3.2E-03 0.400 None 0.958 214 1 1989 2020
Entrez Id: 100125288
Gene Symbol: ZGLP1
ZGLP1
P0C6A0 zinc finger GATA like protein 1 186 0.512 0.808 0.39 0.100 None 0.985 202 0 1993 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 0.950 179 7 1995 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.921 164 8 1994 2020
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 340 0.461 0.808 0.15 1.000 None 0.942 155 31 1992 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.300 None 0.951 144 4 1993 2020
Entrez Id: 169026
Gene Symbol: SLC30A8
SLC30A8
Q8IWU4 solute carrier family 30 member 8 Transporter 63 0.623 0.731 7.4E-12 0.500 None 0.963 135 12 2007 2019
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.700 None 0.978 134 2 1983 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.700 None 0.962 133 7 1985 2020
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 233 0.488 0.769 2.4E-02 0.900 None 0.939 132 8 1993 2019
Entrez Id: 79068
Gene Symbol: FTO
FTO
Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.500 None 0.954 130 31 2007 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.969 129 3 2002 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.600 None 0.952 124 2 1996 2020
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 86 0.617 0.615 1.6E-02 0.700 None 0.984 124 91 2007 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.100 None 0.965 114 1 1985 2020
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Q9HC96 calpain 10 Enzyme 58 0.621 0.577 6.9E-13 0.700 None 0.926 108 8 2000 2019
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 281 0.485 0.769 4.5E-08 0.500 None 0.972 106 27 2008 2019