Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 340 0.461 0.808 0.15 1.000 None 0.942 155 31 1992 2019
Entrez Id: 5078
Gene Symbol: PAX4
PAX4
O43316 paired box 4 63 0.644 0.423 4.2E-04 1.000 limited 0.857 21 3 1999 2019
Entrez Id: 5506
Gene Symbol: PPP1R3A
PPP1R3A
Q16821 protein phosphatase 1 regulatory subunit 3A Enzyme modulator 37 0.711 0.577 9.3E-16 1.000 limited 0.929 14 2 1994 2018
Entrez Id: 208
Gene Symbol: AKT2
AKT2
P31751 AKT serine/threonine kinase 2 Kinase 264 0.474 0.769 0.64 0.960 None 1.000 10 2 2001 2018
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase Kinase 210 0.523 0.808 0.63 0.900 strong 0.953 192 11 1992 2020
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 233 0.488 0.769 2.4E-02 0.900 None 0.939 132 8 1993 2019
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 292 0.478 0.846 0.96 0.900 strong 0.954 130 22 1995 2019
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 218 0.529 0.615 1.1E-02 0.900 strong 0.943 106 14 1996 2019
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
P14672 solute carrier family 2 member 4 Transporter 158 0.528 0.769 4.7E-05 0.800 None 0.951 81 2 1990 2020
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B Nucleic acid binding 279 0.473 0.808 1.00 0.800 None 0.978 46 10 1998 2019
Entrez Id: 4760
Gene Symbol: NEUROD1
NEUROD1
Q13562 neuronal differentiation 1 Enzyme 135 0.543 0.808 0.77 0.800 strong 0.920 25 3 1999 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 257 0.485 0.846 1.00 0.700 None 0.965 402 34 2006 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.700 None 0.953 279 20 1998 2020
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.700 None 0.978 134 2 1983 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.700 None 0.962 133 7 1985 2020
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 86 0.617 0.615 1.6E-02 0.700 None 0.984 124 91 2007 2019
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Q9HC96 calpain 10 Enzyme 58 0.621 0.577 6.9E-13 0.700 None 0.926 108 8 2000 2019
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 317 0.474 0.846 8.0E-24 0.700 None 0.900 60 11 1995 2018
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 247 0.498 0.808 5.0E-08 0.700 moderate 0.814 59 8 2000 2019
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 185 0.530 0.654 1.8E-02 0.700 None 0.956 45 7 1998 2019
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.700 None 0.975 40 2 1997 2017
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
O76024 wolframin ER transmembrane glycoprotein 185 0.528 0.846 1.6E-38 0.700 strong 0.974 38 14 2002 2020
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
P11168 solute carrier family 2 member 2 Transporter 123 0.572 0.692 3.4E-08 0.700 None 0.839 31 6 1990 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.700 None 1.000 26 3 2002 2020
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5
O95622 adenylate cyclase 5 103 0.617 0.577 1.00 0.700 None 0.947 19 3 2002 2019