Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.600 None 0.914 152 6 1994 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.600 None 0.960 100 3 1989 2020
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.300 None 0.990 99 0 1995 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.600 None 0.990 99 1 1996 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.400 None 0.929 70 4 1996 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.300 None 0.957 47 3 1997 2020
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2
P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.100 None 0.955 44 0 2013 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.600 None 1.000 42 0 2010 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 0.976 42 1 1999 2019
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.300 None 0.974 38 0 1998 2020
Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
P15121 aldo-keto reductase family 1 member B Enzyme 220 0.491 0.885 2.0E-05 0.100 None 0.971 34 1 1997 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.600 None 0.941 34 7 2000 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 33 0 2010 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.400 None 0.970 33 8 2004 2019
Entrez Id: 23771
Gene Symbol: DIANPH
DIANPH
diabetic nephropathy 35 0.678 0.500 0.100 None 1.000 32 0 2006 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.600 None 0.969 32 1 2000 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.300 None 0.867 30 1 1996 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.967 30 3 1999 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.300 None 1.000 29 5 2002 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.929 28 2 1996 2019
Entrez Id: 84735
Gene Symbol: CNDP1
CNDP1
Q96KN2 carnosine dipeptidase 1 Enzyme 49 0.656 0.538 1.2E-09 0.400 None 0.929 28 1 2005 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 1.000 26 2 2011 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.600 None 0.962 26 2 2003 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 0.960 25 0 2015 2020
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.300 None 0.960 25 3 2003 2019