Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.100 None 0.984 123 1 1988 2020
Entrez Id: 1859
Gene Symbol: DYRK1A
DYRK1A
Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 212 0.533 0.769 1.00 0.300 None 0.991 109 0 1996 2020
Entrez Id: 2623
Gene Symbol: GATA1
GATA1
P15976 GATA binding protein 1 264 0.483 0.808 0.95 0.400 None 0.981 104 0 2002 2020
Entrez Id: 1827
Gene Symbol: RCAN1
RCAN1
P53805 regulator of calcineurin 1 Signaling 110 0.572 0.808 1.7E-02 0.400 None 0.965 57 0 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.878 49 4 1999 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.400 None 1.000 48 0 1977 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.955 44 1 1994 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.100 None 0.970 33 0 1997 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.100 None 0.969 32 0 1986 2019
Entrez Id: 875
Gene Symbol: CBS
CBS
P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.100 None 0.935 31 6 1985 2019
Entrez Id: 2114
Gene Symbol: ETS2
ETS2
P15036 ETS proto-oncogene 2, transcription factor Transcription factor 115 0.548 0.808 1.00 0.100 None 1.000 26 4 1987 2014
Entrez Id: 5069
Gene Symbol: PAPPA
PAPPA
Q13219 pappalysin 1 125 0.558 0.692 0.16 0.100 None 0.923 26 0 1995 2018
Entrez Id: 102724560
Gene Symbol: CBSL
CBSL
P0DN79 P35520 cystathionine beta-synthase like 129 0.540 0.808 0.100 None 0.960 25 0 1985 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.400 None 1.000 24 0 1988 2019
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.100 None 0.875 24 2 2000 2017
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.100 None 0.824 17 2 2003 2014
Entrez Id: 1826
Gene Symbol: DSCAM
DSCAM
O60469 DS cell adhesion molecule 45 0.686 0.385 1.00 0.100 None 1.000 17 0 1998 2019
Entrez Id: 6493
Gene Symbol: SIM2
SIM2
Q14190 SIM bHLH transcription factor 2 Transcription factor 69 0.619 0.731 0.20 0.100 None 1.000 16 2 1995 2015
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1
P41440 solute carrier family 19 member 1 Transporter 155 0.523 0.692 6.5E-06 0.400 None 0.786 14 7 2003 2013
Entrez Id: 64109
Gene Symbol: CRLF2
CRLF2
Q9HC73 cytokine receptor like factor 2 Signaling 61 0.615 0.538 3.3E-07 0.100 None 1.000 14 0 2009 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.100 None 1.000 13 0 1999 2020
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
microRNA 155 584 0.384 0.885 0.400 None 1.000 12 0 2007 2019
Entrez Id: 5981
Gene Symbol: RFC1
RFC1
P35251 replication factor C subunit 1 144 0.541 0.808 0.97 0.100 None 0.833 12 0 2005 2017
Entrez Id: 2078
Gene Symbol: ERG
ERG
P11308 ETS transcription factor ERG Transcription factor 298 0.453 0.808 0.96 0.100 None 1.000 11 0 1996 2020
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.100 None 1.000 10 0 2007 2017