Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7051
Gene Symbol: TGM1
TGM1
P22735 transglutaminase 1 Enzyme 117 0.565 0.769 2.3E-13 0.310 None 1.000 2 0 2005 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.240 None 1.000 5 0 2009 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.210 None 1.000 1 0 2018 2018
Entrez Id: 5360
Gene Symbol: PLTP
PLTP
P55058 phospholipid transfer protein 62 0.633 0.654 9.0E-09 0.200 None 0 0
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.070 None 1.000 7 0 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.060 None 1.000 6 0 2014 2019
Entrez Id: 79054
Gene Symbol: TRPM8
TRPM8
Q7Z2W7 transient receptor potential cation channel subfamily M member 8 Ion channel 127 0.553 0.808 4.6E-29 0.050 None 1.000 5 0 2017 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.040 None 1.000 4 0 2015 2019
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.040 None 1.000 4 0 2017 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.040 None 1.000 4 0 2008 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.040 None 1.000 4 0 2017 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.040 None 1.000 4 0 2017 2019
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 480 0.407 0.885 1.00 0.030 None 1.000 3 0 2017 2018
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
Q96DR5 BPI fold containing family A member 2 80 0.608 0.808 8.0E-07 0.030 None 1.000 3 0 2018 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.030 None 1.000 3 0 2017 2018
Entrez Id: 6737
Gene Symbol: TRIM21
TRIM21
P19474 tripartite motif containing 21 229 0.485 0.808 3.4E-09 0.020 None 1.000 2 0 2018 2018
Entrez Id: 1773
Gene Symbol: DNASE1
DNASE1
P24855 deoxyribonuclease 1 180 0.505 0.846 7.0E-21 0.020 None 1.000 2 0 2015 2020
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.020 None 1.000 2 0 2019 2020
Entrez Id: 7114
Gene Symbol: TMSB4X
TMSB4X
P62328 thymosin beta 4 X-linked 130 0.541 0.692 0.41 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.020 None 1.000 2 0 2013 2015
Entrez Id: 5080
Gene Symbol: PAX6
PAX6
P26367 paired box 6 340 0.450 0.769 1.00 0.020 None 1.000 2 0 2013 2014
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.020 None 1.000 2 0 2013 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.020 None 1.000 2 0 2017 2018
Entrez Id: 171389
Gene Symbol: NLRP6
NLRP6
P59044 NLR family pyrin domain containing 6 58 0.628 0.769 2.7E-04 0.020 None 1.000 2 0 2017 2018