Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.200 None 1.000 10 0 1997 2011
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.530 None 1.000 5 0 2006 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.520 None 1.000 4 0 2009 2018
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.200 None 1.000 3 0 2012 2019
Entrez Id: 4040
Gene Symbol: LRP6
LRP6
O75581 LDL receptor related protein 6 134 0.536 0.808 0.70 0.200 None 1.000 2 0 2014 2015
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
P32245 melanocortin 4 receptor G-protein coupled receptor 149 0.535 0.692 9.2E-04 0.200 None 1.000 2 0 2005 2011
Entrez Id: 23175
Gene Symbol: LPIN1
LPIN1
Q14693 lipin 1 86 0.601 0.692 6.5E-13 0.020 None 1.000 2 0 2014 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.210 None 1.000 2 0 2009 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.210 None 1.000 2 0 2006 2009
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
P17931 galectin 3 Signaling 557 0.392 0.846 2.3E-05 0.200 None 1.000 2 0 2006 2008
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
P07858 cathepsin B Enzyme 304 0.457 0.846 5.9E-11 0.200 None 1.000 2 0 2007 2008
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.200 None 1.000 2 0 2012 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.200 None 1.000 2 0 2011 2015
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 41 0.686 0.423 8.4E-12 0.210 None 1.000 2 0 2007 2010
Entrez Id: 54681
Gene Symbol: P4HTM
P4HTM
Q9NXG6 prolyl 4-hydroxylase, transmembrane 59 0.666 0.500 3.9E-09 0.010 None 1.000 1 0 2019 2019
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.200 None 1.000 1 0 2008 2008
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
P36955 serpin family F member 1 Enzyme modulator 294 0.460 0.846 7.8E-08 0.200 None 1.000 1 0 2009 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.200 None 1.000 1 0 2011 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.200 None 1.000 1 0 2008 2008
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
Q9Y3D6 fission, mitochondrial 1 40 0.663 0.769 1.3E-05 0.200 None 1.000 1 0 2014 2014
Entrez Id: 5009
Gene Symbol: OTC
OTC
P00480 ornithine carbamoyltransferase 135 0.565 0.846 0.87 0.200 None 1.000 1 0 2009 2009
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 236 0.510 0.846 0.99 0.200 None 1.000 1 0 2014 2014
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.200 None 1.000 1 0 2011 2011
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.200 None 1.000 1 0 2014 2014