Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2303
Gene Symbol: FOXC2
FOXC2 		Q99958 forkhead box C2 Transcription factor 168 0.515 0.731 0.13 0.100 None 0 0
Entrez Id: 286827
Gene Symbol: TRIM59
TRIM59 		Q8IWR1 tripartite motif containing 59 74 0.599 0.577 1.5E-03 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 2313
Gene Symbol: FLI1
FLI1 		Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 318 0.468 0.692 0.99 0.010 None < 0.001 1 0 2009 2009
Entrez Id: 835
Gene Symbol: CASP2
CASP2 		P42575 caspase 2 Enzyme 105 0.565 0.731 1.5E-03 0.010 None < 0.001 1 0 2012 2012
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1 		P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.130 None 0.667 3 0 1999 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.040 None 0.750 4 1 1985 2006
Entrez Id: 5055
Gene Symbol: SERPINB2
SERPINB2 		P05120 serpin family B member 2 Enzyme modulator 183 0.502 0.808 6.4E-12 0.060 None 0.833 6 0 1988 2000
Entrez Id: 2335
Gene Symbol: FN1
FN1 		P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.100 None 0.909 11 0 1986 2017
Entrez Id: 4323
Gene Symbol: MMP14
MMP14 		P50281 matrix metallopeptidase 14 Enzyme 340 0.447 0.769 1.00 0.100 None 0.923 13 0 1999 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 24 1 1990 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 23 0 1992 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 14 0 1988 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 1.000 14 0 1991 2019
Entrez Id: 8872
Gene Symbol: CDC123
CDC123 		O75794 cell division cycle 123 21 0.780 0.231 1.1E-05 0.100 None 1.000 11 0 1978 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 10 1 1999 2019
Entrez Id: 5340
Gene Symbol: PLG
PLG 		P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.100 None 1.000 10 0 1987 2000
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.070 None 1.000 7 0 2007 2019
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		P18146 early growth response 1 Nucleic acid binding 378 0.433 0.923 0.35 0.060 None 1.000 6 0 1998 2006
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		P00750 plasminogen activator, tissue type Enzyme 392 0.445 0.885 5.7E-05 0.060 None 1.000 6 0 1988 2000
Entrez Id: 2821
Gene Symbol: GPI
GPI 		P06744 glucose-6-phosphate isomerase Enzyme 218 0.491 0.769 2.8E-06 0.050 None 1.000 5 0 1991 2010
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.050 None 1.000 5 0 1987 1997
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2 		P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 404 0.425 0.846 0.79 0.050 None 1.000 5 0 2005 2017
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.050 None 1.000 5 0 2007 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.040 None 1.000 4 0 1991 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.040 None 1.000 4 1 2012 2019