Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch receptor 2 384 0.441 0.808 1.00 0.380 None 1.000 9 0 2007 2018
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.380 None 1.000 8 0 1987 2018
Entrez Id: 3014
Gene Symbol: H2AX
H2AX
P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.370 None 1.000 8 0 2003 2019
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
Q05397 protein tyrosine kinase 2 Kinase 205 0.497 0.808 1.00 0.370 None 1.000 8 0 2002 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.370 None 1.000 7 0 1999 2018
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.370 None 1.000 7 0 2010 2019
Entrez Id: 7158
Gene Symbol: TP53BP1
TP53BP1
Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 158 0.520 0.731 1.00 0.360 None 1.000 7 0 2010 2019
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
Q00534 cyclin dependent kinase 6 Kinase 266 0.471 0.731 0.98 0.350 None 1.000 6 0 2000 2017
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
P43235 cathepsin K Enzyme 221 0.497 0.808 3.1E-05 0.350 None 1.000 5 0 2014 2018
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 446 0.422 0.808 1.00 0.350 None 1.000 5 0 2004 2014
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 Enzyme 315 0.445 0.808 6.8E-18 0.340 None 1.000 6 0 2005 2017
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 Enzyme 225 0.488 0.731 1.1E-02 0.340 None 1.000 5 0 2004 2020
Entrez Id: 182
Gene Symbol: JAG1
JAG1
P78504 jagged canonical Notch ligand 1 420 0.429 0.808 1.00 0.340 None 1.000 5 0 2010 2018
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.340 None 1.000 5 0 1995 2019
Entrez Id: 8434
Gene Symbol: RECK
RECK
O95980 reversion inducing cysteine rich protein with kazal motifs Enzyme modulator 123 0.547 0.731 1.9E-10 0.340 None 1.000 5 0 2006 2015
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 Transcription factor 110 0.551 0.692 5.0E-02 0.330 None 1.000 4 0 2009 2018
Entrez Id: 5371
Gene Symbol: PML
PML
P29590 promyelocytic leukemia 274 0.477 0.846 0.21 0.330 None 1.000 4 0 2009 2017
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
P25440 bromodomain containing 2 Epigenetic regulator 303 0.450 0.808 1.00 0.330 None 1.000 4 0 1999 2018
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1
Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.330 None 1.000 4 0 2013 2020
Entrez Id: 8358
Gene Symbol: H3C2
H3C2
P68431 H3 clustered histone 2 43 0.653 0.423 1.5E-05 0.330 None 1.000 4 0 2012 2018
Entrez Id: 8553
Gene Symbol: BHLHE40
BHLHE40
O14503 basic helix-loop-helix family member e40 Transcription factor 113 0.544 0.731 0.99 0.330 None 1.000 4 0 2001 2016
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.330 None 1.000 4 0 2012 2019
Entrez Id: 1616
Gene Symbol: DAXX
DAXX
Q9UER7 death domain associated protein 137 0.544 0.692 9.9E-02 0.330 None 1.000 3 0 2015 2018
Entrez Id: 2195
Gene Symbol: FAT1
FAT1
Q14517 FAT atypical cadherin 1 178 0.508 0.808 1.2E-12 0.330 None 1.000 3 0 2013 2018
Entrez Id: 26136
Gene Symbol: TES
TES
Q9UGI8 testin LIM domain protein Cellular structure 67 0.604 0.692 1.0E-15 0.330 None 1.000 3 0 2007 2013