Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 159 0.529 0.808 1.00 0.800 strong 0.929 14 1 1996 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.600 None 0.984 258 2 1992 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.600 None 0.991 111 2 1992 2020
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
P16860 natriuretic peptide B 193 0.513 0.808 9.9E-06 0.600 None 0.986 73 0 1991 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 0.972 71 0 1996 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.600 None 1.000 52 0 2000 2019
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
P08588 adrenoceptor beta 1 G-protein coupled receptor 130 0.555 0.769 2.9E-06 0.600 None 0.940 50 2 1991 2019
Entrez Id: 156
Gene Symbol: GRK2
GRK2
P25098 G protein-coupled receptor kinase 2 Kinase 159 0.532 0.654 1.00 0.600 None 0.980 49 0 1994 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.600 None 0.976 42 1 1994 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.600 None 0.971 34 1 1997 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.600 None 0.926 27 3 2003 2019
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
P01160 natriuretic peptide A 217 0.505 0.769 5.5E-04 0.600 None 1.000 20 1 1989 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.600 None 1.000 15 0 2004 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.600 None 1.000 12 0 2005 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.590 None 0.909 11 0 1998 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.570 None 0.917 12 0 2005 2020
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
O14793 myostatin Signaling 159 0.528 0.731 0.51 0.570 None 1.000 8 0 2006 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.560 None 1.000 8 0 2005 2019
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
P13945 adrenoceptor beta 3 G-protein coupled receptor 142 0.533 0.731 2.5E-07 0.520 None 1.000 5 0 2004 2017
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.500 None 1.000 13 0 2005 2019
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 61 0.647 0.538 2.7E-10 0.500 None 1.000 2 0 2007 2009
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.500 None 1.000 2 0 2003 2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.480 None 1.000 9 2 2009 2019
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
P45379 troponin T2, cardiac type Cellular structure 79 0.601 0.423 2.0E-03 0.410 None 1.000 3 1 2002 2007
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.400 None 0.977 171 0 1982 2020