Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
P29475 nitric oxide synthase 1 521 0.408 0.885 1.00 0.500 None 1.000 2 0 2009 2013
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.500 None 1.000 2 0 2008 2012
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.500 None 1.000 2 0 2005 2016
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
O95140 mitofusin 2 Enzyme 334 0.471 0.846 0.99 0.500 None 1.000 1 0 2017 2017
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.400 None 1.000 13 1 2008 2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.380 None 1.000 17 0 1996 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.380 None 1.000 10 0 2003 2019
Entrez Id: 5024
Gene Symbol: P2RX3
P2RX3
P56373 purinergic receptor P2X 3 Ion channel 125 0.565 0.769 1.0E-06 0.360 None 1.000 7 0 2009 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.350 None 1.000 7 0 2003 2019
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin Signaling 103 0.603 0.577 1.5E-02 0.340 None 1.000 6 0 1998 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.340 None 1.000 5 0 2009 2018
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
P25103 tachykinin receptor 1 G-protein coupled receptor 217 0.502 0.885 3.8E-04 0.330 None 1.000 5 0 2005 2019
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
Q9H2X9 solute carrier family 12 member 5 Transporter 135 0.570 0.654 1.00 0.330 None 1.000 4 0 2010 2018
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 422 0.457 0.808 2.2E-16 0.330 None 1.000 4 0 2008 2018
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
P45983 mitogen-activated protein kinase 8 Kinase 520 0.397 0.885 1.00 0.330 None 1.000 4 0 2016 2019
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
P34998 corticotropin releasing hormone receptor 1 183 0.517 0.769 3.8E-05 0.330 None 1.000 3 0 2017 2018
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
Q02156 protein kinase C epsilon Kinase 112 0.597 0.692 1.00 0.320 None 1.000 5 0 2001 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.320 None 1.000 3 0 1997 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.320 None 1.000 3 0 2010 2018
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.320 None 1.000 3 0 2007 2018
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.320 None 1.000 3 0 2003 2018
Entrez Id: 22953
Gene Symbol: P2RX2
P2RX2
Q9UBL9 purinergic receptor P2X 2 Ion channel 99 0.585 0.769 9.7E-13 0.320 None 1.000 3 0 2009 2018
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.310 None 1.000 3 0 2008 2017
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.310 None 1.000 3 0 2006 2008
Entrez Id: 5731
Gene Symbol: PTGER1
PTGER1
P34995 prostaglandin E receptor 1 G-protein coupled receptor 44 0.674 0.538 9.7E-04 0.310 None 1.000 2 0 2001 2018