Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.500 0.919 146 21 1982 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.500 0.955 73 2 1985 2018
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 232 0.477 0.724 1.6E-16 0.500 0.943 55 1 1987 2016
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 hydrolase; protease 101 0.572 0.552 1.9E-17 0.500 0.917 51 11 2003 2017
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase hydrolase; storage protein 203 0.504 0.724 7.2E-10 0.460 1.000 7 0 1993 2012
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1
P22680 cytochrome P450 family 7 subfamily A member 1 oxidoreductase 54 0.630 0.379 2.8E-04 0.420 1.000 3 0 1993 2012
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 69 0.584 0.621 1.00 0.400 0.900 12 0 1996 2016
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.400 0.909 12 0 1991 2016
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 transporter 236 0.484 0.793 3.5E-12 0.350 1.000 6 0 2002 2018
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
P19320 vascular cell adhesion molecule 1 232 0.466 0.793 0.74 0.340 1.000 5 0 1994 2011
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.340 0.750 5 0 2000 2008
Entrez Id: 6401
Gene Symbol: SELE
SELE
P16581 selectin E 208 0.479 0.793 7.0E-10 0.320 1.000 3 0 2003 2009
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.320 1.000 3 0 2012 2016
Entrez Id: 8013
Gene Symbol: NR4A3
NR4A3
Q92570 nuclear receptor subfamily 4 group A member 3 receptor; transcription factor 108 0.545 0.759 0.90 0.310 1.000 2 0 2006 2010
Entrez Id: 1489
Gene Symbol: CTF1
CTF1
Q16619 cardiotrophin 1 40 0.667 0.345 3.6E-02 0.300 1 0 2012 2012
Entrez Id: 653361
Gene Symbol: NCF1
NCF1
P14598 neutrophil cytosolic factor 1 129 0.546 0.759 1.7E-04 0.300 1 0 2004 2004
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 222 0.510 0.759 1.00 0.300 1 0 2012 2012
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 signaling molecule 419 0.417 0.828 0.46 0.300 1 0 2005 2005
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.300 1 0 2003 2003
Entrez Id: 27035
Gene Symbol: NOX1
NOX1
Q9Y5S8 NADPH oxidase 1 oxidoreductase 68 0.607 0.586 9.9E-08 0.300 1 0 2011 2011
Entrez Id: 4638
Gene Symbol: MYLK
MYLK
Q15746 myosin light chain kinase 105 0.565 0.621 7.5E-11 0.300 1 0 2011 2011
Entrez Id: 1066
Gene Symbol: CES1
CES1
P23141 carboxylesterase 1 hydrolase; protease 48 0.630 0.655 2.3E-13 0.300 1 0 2004 2004
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 116 0.555 0.655 1.0E-23 0.200 0.929 14 0 1995 2016
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
Q5SW96 low density lipoprotein receptor adaptor protein 1 signaling molecule 49 0.656 0.310 7.7E-06 0.190 0.600 9 0 2002 2014
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8
Q9H221 ATP binding cassette subfamily G member 8 transporter 95 0.584 0.448 2.0E-20 0.160 1.000 6 1 2004 2013