Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.900 strong 0.982 955 1292 1964 2020
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.700 strong 0.986 140 36 1979 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.500 strong 0.977 171 38 2003 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.400 None 0.875 16 1 1991 2020
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 64 0.641 0.538 6.5E-06 0.400 strong 1.000 13 1 2002 2019
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.390 None 1.000 10 2 1997 2011
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.380 None 1.000 9 3 1993 2016
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.370 None 1.000 8 0 2000 2019
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.360 None 1.000 7 1 1975 2016
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.330 None 1.000 4 1 2003 2019
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
Q9H222 ATP binding cassette subfamily G member 5 Transporter 108 0.592 0.577 3.1E-21 0.330 strong 1.000 4 0 2010 2018
Entrez Id: 5445
Gene Symbol: PON2
PON2
Q15165 paraoxonase 2 117 0.566 0.808 5.4E-05 0.320 None 1.000 3 1 2001 2006
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.320 None 1.000 3 0 2005 2014
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8
Q9H221 ATP binding cassette subfamily G member 8 Transporter 116 0.573 0.538 2.4E-20 0.320 strong 1.000 3 0 2009 2019
Entrez Id: 337
Gene Symbol: APOA4
APOA4
P06727 apolipoprotein A4 88 0.582 0.577 5.5E-06 0.320 None 1.000 3 0 1998 2005
Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2
Q12772 sterol regulatory element binding transcription factor 2 112 0.566 0.577 0.21 0.310 None 1.000 2 0 2002 2018
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.300 None 1.000 1 0 2005 2005
Entrez Id: 336
Gene Symbol: APOA2
APOA2
P02652 apolipoprotein A2 Transporter 77 0.582 0.769 4.5E-02 0.300 None 1.000 1 0 2002 2002
Entrez Id: 2710
Gene Symbol: GK
GK
P32189 glycerol kinase Kinase 55 0.656 0.577 0.99 0.200 None 1.000 1 0 1999 1999
Entrez Id: 26228
Gene Symbol: STAP1
STAP1
Q9ULZ2 signal transducing adaptor family member 1 Receptor 8 0.792 0.231 1.7E-05 0.140 None 1.000 5 1 2016 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.100 None 0.953 43 1 1991 2019
Entrez Id: 102465534
Gene Symbol: MIR6886
MIR6886
microRNA 6886 6 0.861 0.077 0.100 None 1.000 17 256 1995 2016
Entrez Id: 25959
Gene Symbol: KANK2
KANK2
Q63ZY3 KN motif and ankyrin repeat domains 2 63 0.638 0.615 4.5E-02 0.100 None 1.000 1 3 2013 2013
Entrez Id: 5589
Gene Symbol: PRKCSH
PRKCSH
P14314 protein kinase C substrate 80K-H Enzyme 44 0.674 0.538 1.0E-07 0.100 None 1.000 1 1 2013 2013
Entrez Id: 55552
Gene Symbol: ZNF823
ZNF823
P16415 zinc finger protein 823 4 0.931 0.115 0.38 0.100 None 1.000 1 2 2013 2013