Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.700 None 1.000 27 2 1994 2019
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta Kinase 317 0.453 0.885 1.00 0.540 None 1.000 6 0 1999 2019
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase Kinase 210 0.523 0.808 0.63 0.500 None 1.000 127 23 1992 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.500 None 0.966 29 0 1984 2019
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 292 0.478 0.846 0.96 0.500 None 0.964 28 5 1996 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.500 None 1.000 23 1 2005 2020
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.400 None 0.966 116 0 1975 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.400 None 1.000 25 0 2009 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.400 None 1.000 23 0 2008 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.400 None 1.000 18 1 2004 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.400 None 1.000 14 0 2009 2019
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 185 0.530 0.654 1.8E-02 0.400 None 1.000 14 0 1999 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.400 None 1.000 13 1 2001 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.400 None 1.000 13 0 2010 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.350 None 1.000 5 0 2003 2017
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.330 None 1.000 11 1 1986 2018
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.330 None 0.800 5 0 2010 2018
Entrez Id: 6667
Gene Symbol: SP1
SP1
P08047 Sp1 transcription factor Nucleic acid binding 209 0.493 0.769 1.00 0.330 None 1.000 4 0 2001 2019
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.310 None 1.000 2 0 2013 2018
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 Enzyme 290 0.458 0.923 3.9E-05 0.310 None 1.000 2 0 2004 2010
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
P28845 hydroxysteroid 11-beta dehydrogenase 1 163 0.520 0.731 0.42 0.310 None 1.000 2 0 2004 2017
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 Transcription factor 84 0.626 0.654 1.00 0.310 None 0.500 2 0 2008 2019
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 528 0.396 0.846 0.85 0.310 None 1.000 2 0 2018 2018
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.300 None 0.919 37 0 1999 2019
Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
P15121 aldo-keto reductase family 1 member B Enzyme 220 0.491 0.885 2.0E-05 0.300 None 1.000 28 0 1998 2020