Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.200 None 1.000 32 0 2006 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 14 0 2000 2019
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.200 None 1.000 10 0 1987 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.080 None 1.000 8 0 2002 2020
Entrez Id: 790
Gene Symbol: CAD
CAD
P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 249 0.482 0.846 1.00 0.070 None 0.714 7 0 1975 2019
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.460 None 1.000 7 0 1994 2020
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.060 None 1.000 6 0 2018 2019
Entrez Id: 341
Gene Symbol: APOC1
APOC1
P02654 apolipoprotein C1 95 0.581 0.577 0.22 0.060 None 0.833 6 0 1998 2018
Entrez Id: 948
Gene Symbol: CD36
CD36
P16671 CD36 molecule Receptor 351 0.446 0.846 1.1E-60 0.060 None 1.000 6 0 2004 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.250 None 1.000 6 0 2002 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.250 None 1.000 6 0 2005 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.530 None 1.000 5 0 2001 2018
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1
Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 371 0.460 0.808 1.00 0.050 None 1.000 5 0 2018 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.050 None 1.000 5 0 2007 2018
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.340 None 1.000 5 0 1977 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.240 None 0.800 5 0 2013 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.050 None 1.000 5 0 2017 2018
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.050 None 1.000 5 0 2014 2020
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 325 0.453 0.846 0.14 0.050 None 1.000 5 0 2016 2019
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.050 None 1.000 5 0 2017 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.050 None 1.000 5 0 2015 2019
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.050 None 1.000 5 0 2014 2020
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
P14672 solute carrier family 2 member 4 Transporter 158 0.528 0.769 4.7E-05 0.040 None 1.000 4 0 2005 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.330 None 1.000 4 0 1984 2019
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.040 None 1.000 4 0 1994 2019