Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7172
Gene Symbol: TPMT
TPMT 		P51580 thiopurine S-methyltransferase 83 0.593 0.692 7.1E-06 0.100 None 1.000 56 3 1999 2019
Entrez Id: 51561
Gene Symbol: IL23A
IL23A 		Q9NPF7 interleukin 23 subunit alpha Signaling 427 0.415 0.846 0.36 0.100 None 1.000 40 0 2005 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 34 1 2010 2019
Entrez Id: 50616
Gene Symbol: IL22
IL22 		Q9GZX6 interleukin 22 551 0.393 0.885 1.9E-04 0.100 None 1.000 28 0 2005 2020
Entrez Id: 410
Gene Symbol: ARSA
ARSA 		P15289 arylsulfatase A Enzyme 376 0.448 0.923 1.1E-11 0.100 None 1.000 26 0 2009 2020
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.100 None 1.000 23 0 2005 2020
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.100 None 1.000 22 0 2002 2019
Entrez Id: 3587
Gene Symbol: IL10RA
IL10RA 		Q13651 interleukin 10 receptor subunit alpha Receptor 90 0.579 0.692 1.8E-02 0.400 strong 1.000 21 1 2012 2019
Entrez Id: 50941
Gene Symbol: IBD5
IBD5 		inflammatory bowel disease 5 21 0.705 0.538 0.100 None 1.000 20 0 2003 2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.400 None 1.000 19 3 1995 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 1.000 19 0 1994 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 18 0 1998 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.200 None 1.000 17 1 2000 2018
Entrez Id: 345611
Gene Symbol: IRGM
IRGM 		A1A4Y4 immunity related GTPase M 57 0.617 0.538 0.500 None 1.000 16 3 2008 2017
Entrez Id: 3565
Gene Symbol: IL4
IL4 		P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.100 None 1.000 16 1 1994 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.400 None 1.000 16 1 2001 2020
Entrez Id: 27178
Gene Symbol: IL37
IL37 		Q9NZH6 interleukin 37 280 0.459 0.846 1.2E-04 0.100 None 1.000 15 0 2007 2019
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7 		O15105 SMAD family member 7 Transcription factor 269 0.470 0.769 0.55 0.100 None 1.000 15 0 2001 2019
Entrez Id: 3378
Gene Symbol: IBD2
IBD2 		inflammatory bowel disease 2 13 0.805 0.154 0.100 None 1.000 14 0 1998 2012
Entrez Id: 3704
Gene Symbol: ITPA
ITPA 		Q9BY32 inosine triphosphatase Enzyme 77 0.604 0.500 1.0E-07 0.100 None 1.000 14 1 2004 2018
Entrez Id: 130589
Gene Symbol: GALM
GALM 		Q96C23 galactose mutarotase Enzyme 9 0.792 0.192 4.9E-11 0.100 None 1.000 13 0 1998 2009
Entrez Id: 7038
Gene Symbol: TG
TG 		P01266 thyroglobulin Enzyme modulator 240 0.480 0.808 2.9E-59 0.100 None 1.000 13 1 2007 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.200 None 1.000 12 1 2000 2020
Entrez Id: 331
Gene Symbol: XIAP
XIAP 		P98170 X-linked inhibitor of apoptosis Enzyme modulator 321 0.447 0.808 0.92 0.400 strong 1.000 12 0 2012 2020
Entrez Id: 3578
Gene Symbol: IL9
IL9 		P15248 interleukin 9 291 0.461 0.846 8.1E-07 0.100 None 1.000 12 0 2001 2019