Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 0.964 362 1 1992 2020
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Q9UKU7 acyl-CoA dehydrogenase family member 8 Enzyme 203 0.506 0.885 5.6E-14 0.100 None 0.971 240 0 1987 2020
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.500 None 0.949 195 22 1998 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.700 None 0.993 138 4 1995 2020
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.500 None 0.947 75 10 2006 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 0.971 68 1 2003 2020
Entrez Id: 7172
Gene Symbol: TPMT
TPMT
P51580 thiopurine S-methyltransferase 83 0.593 0.692 7.1E-06 0.100 None 1.000 56 3 1999 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.981 52 2 1992 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.980 50 0 1992 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.100 None 0.976 42 2 1993 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.927 41 5 2000 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.100 None 0.976 41 4 2001 2019
Entrez Id: 51561
Gene Symbol: IL23A
IL23A
Q9NPF7 interleukin 23 subunit alpha Signaling 427 0.415 0.846 0.36 0.100 None 1.000 40 0 2005 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.868 38 0 2002 2020
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
Q676U5 autophagy related 16 like 1 120 0.543 0.769 0.96 0.500 None 0.974 38 5 2007 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 0.972 36 2 2006 2019
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
O95150 TNF superfamily member 15 Signaling 143 0.531 0.692 2.8E-03 0.500 None 0.971 35 6 2003 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 34 1 2010 2019
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Q6ZT07 TBC1 domain family member 9 Enzyme 491 0.399 0.846 2.8E-05 0.100 None 0.938 32 0 2003 2018
Entrez Id: 9231
Gene Symbol: DLG5
DLG5
Q8TDM6 discs large MAGUK scaffold protein 5 36 0.686 0.500 1.00 0.100 None 0.903 31 4 2004 2018
Entrez Id: 50616
Gene Symbol: IL22
IL22
Q9GZX6 interleukin 22 551 0.393 0.885 1.9E-04 0.100 None 1.000 28 0 2005 2020
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.963 27 2 2000 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.100 None 0.963 27 3 2002 2020
Entrez Id: 410
Gene Symbol: ARSA
ARSA
P15289 arylsulfatase A Enzyme 376 0.448 0.923 1.1E-11 0.100 None 1.000 26 0 2009 2020
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.100 None 1.000 23 0 2005 2020