Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.970 33 1 1992 2020
Entrez Id: 7507
Gene Symbol: XPA
XPA
P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 209 0.520 0.846 7.9E-05 0.100 None 0 2
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.090 None 1.000 9 0 1999 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.050 None 1.000 5 0 1997 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.040 None 1.000 4 0 1999 2018
Entrez Id: 4118
Gene Symbol: MAL
MAL
P21145 mal, T cell differentiation protein Transporter 102 0.570 0.577 0.83 0.040 None 1.000 4 0 2018 2019
Entrez Id: 203
Gene Symbol: AK1
AK1
P00568 adenylate kinase 1 Kinase 20 0.711 0.500 2.7E-02 0.030 None 0.667 3 0 2018 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.030 None 1.000 3 0 1998 2010
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.030 None 1.000 3 0 1999 2018
Entrez Id: 3014
Gene Symbol: H2AX
H2AX
P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.020 None 1.000 2 0 2009 2018
Entrez Id: 205
Gene Symbol: AK4
AK4
P27144 adenylate kinase 4 Kinase 27 0.705 0.462 0.13 0.020 None 1.000 2 0 2019 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.020 None 0.500 2 2 2009 2016
Entrez Id: 50808
Gene Symbol: AK3
AK3
Q9UIJ7 adenylate kinase 3 Kinase 32 0.691 0.462 1.1E-04 0.020 None 1.000 2 0 2019 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2010 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.020 None 1.000 2 0 2002 2010
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.020 None 1.000 2 0 2015 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.020 None 1.000 2 0 2007 2018
Entrez Id: 3632
Gene Symbol: INPP5A
INPP5A
Q14642 inositol polyphosphate-5-phosphatase A Enzyme 22 0.743 0.385 0.98 0.020 None 1.000 2 0 2010 2020
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.020 None 1.000 2 0 2005 2008
Entrez Id: 51284
Gene Symbol: TLR7
TLR7
Q9NYK1 toll like receptor 7 276 0.464 0.885 0.98 0.020 None 1.000 2 0 2004 2014
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.020 None 1.000 2 0 2008 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.020 None 1.000 2 0 2012 2013
Entrez Id: 10850
Gene Symbol: CCL27
CCL27
Q9Y4X3 C-C motif chemokine ligand 27 Signaling 185 0.502 0.846 1.4E-02 0.020 None 1.000 2 0 2007 2019
Entrez Id: 3371
Gene Symbol: TNC
TNC
P24821 tenascin C 369 0.433 0.846 1.3E-07 0.020 None 1.000 2 0 2006 2006