Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.200 None 1.000 17 0 2010 2020
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.100 None 0.941 17 0 2009 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.400 None 1.000 17 0 2010 2020
Entrez Id: 81494
Gene Symbol: CFHR5
CFHR5
Q9BXR6 complement factor H related 5 43 0.659 0.385 2.1E-32 0.100 None 0.882 17 1 2010 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 1.000 16 0 2013 2019
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
Q9BYF1 angiotensin I converting enzyme 2 Enzyme 253 0.477 0.769 1.00 0.100 None 1.000 16 0 2004 2018
Entrez Id: 7225
Gene Symbol: TRPC6
TRPC6
Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 166 0.514 0.692 3.0E-07 0.300 None 1.000 16 0 2007 2019
Entrez Id: 1287
Gene Symbol: COL4A5
COL4A5
P29400 collagen type IV alpha 5 chain 124 0.553 0.654 1.00 0.100 None 0.933 15 1 1992 2019
Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
P15121 aldo-keto reductase family 1 member B Enzyme 220 0.491 0.885 2.0E-05 0.100 None 1.000 15 0 1996 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 15 0 2013 2020
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
P98161 polycystin 1, transient receptor potential channel interacting 217 0.493 0.769 1.00 0.100 None 1.000 15 0 2002 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.100 None 1.000 15 0 2004 2019
Entrez Id: 1285
Gene Symbol: COL4A3
COL4A3
Q01955 collagen type IV alpha 3 chain 119 0.552 0.692 1.1E-12 0.100 None 0.857 14 2 1995 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.100 None 1.000 14 0 1998 2019
Entrez Id: 5311
Gene Symbol: PKD2
PKD2
Q13563 polycystin 2, transient receptor potential cation channel Ion channel 122 0.552 0.731 1.7E-04 0.100 None 1.000 14 0 1995 2020
Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
O43707 actinin alpha 4 166 0.508 0.808 1.00 0.100 None 1.000 14 0 2000 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.400 None 1.000 13 1 1996 2019
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
Q96D42 hepatitis A virus cellular receptor 1 217 0.489 0.885 8.5E-07 0.360 None 1.000 13 0 2009 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.846 13 4 1999 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 3 1994 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.100 None 0.750 12 0 1998 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.100 None 1.000 12 0 1998 2019
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.400 None 0.917 12 0 2010 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 11 0 2003 2018
Entrez Id: 567
Gene Symbol: B2M
B2M
P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.480 None 1.000 11 0 1990 2020