Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 0.946 37 0 1994 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.300 None 0.933 30 0 1998 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.960 25 0 1994 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.952 21 0 1994 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.600 None 0.944 18 0 2004 2019
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.100 None 0.941 17 0 2012 2019
Entrez Id: 90678
Gene Symbol: LRSAM1
LRSAM1
Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 63 0.638 0.500 3.1E-13 0.100 None 0.938 16 0 2010 2019
Entrez Id: 8074
Gene Symbol: FGF23
FGF23
Q9GZV9 fibroblast growth factor 23 Signaling 305 0.460 0.731 3.1E-02 0.300 None 0.800 15 0 2001 2020
Entrez Id: 9771
Gene Symbol: RAPGEF5
RAPGEF5
Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 151 0.524 0.769 0.98 0.100 None 1.000 14 0 2000 2019
Entrez Id: 5311
Gene Symbol: PKD2
PKD2
Q13563 polycystin 2, transient receptor potential cation channel Ion channel 122 0.552 0.731 1.7E-04 0.100 None 1.000 14 0 1995 2019
Entrez Id: 23771
Gene Symbol: DIANPH
DIANPH
diabetic nephropathy 35 0.678 0.500 0.100 None 1.000 13 0 2005 2020
Entrez Id: 60498
Gene Symbol: IGAN1
IGAN1
IgA nephropathy 140 0.524 0.808 0.100 None 1.000 13 0 2007 2020
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.300 None 1.000 13 0 1998 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 0.917 12 0 1995 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.280 None 1.000 11 0 1995 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.400 None 1.000 11 0 1998 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.100 None 0.800 10 0 1993 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.090 None 0.889 9 0 2003 2020
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.570 None 0.875 8 0 2006 2020
Entrez Id: 567
Gene Symbol: B2M
B2M
P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.070 None 1.000 7 0 1997 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.070 None 1.000 7 0 2003 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.060 None 0.833 6 0 2003 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.060 None 1.000 6 0 1999 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.050 None 0.800 5 0 2017 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.050 None 1.000 5 0 2004 2016