Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2020 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.050 None 1.000 5 1 2006 2015
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.010 None 1.000 1 0 2004 2004
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.210 None 1.000 3 0 1998 2018
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
P10176 cytochrome c oxidase subunit 8A Enzyme 526 0.400 0.846 0.12 0.050 None 1.000 5 0 1996 2019
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
P54259 atrophin 1 499 0.409 0.885 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.330 None 1.000 4 2 2009 2017
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4512
Gene Symbol: COX1
COX1
P00395 cytochrome c oxidase subunit I Enzyme 421 0.441 0.885 0.020 None 1.000 2 4 2002 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
P33527 ATP binding cassette subfamily C member 1 Transporter 333 0.445 0.808 1.2E-03 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.010 None 1.000 1 0 2013 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 synthesis of cytochrome C oxidase 2 Enzyme 294 0.479 0.846 7.5E-07 0.540 definitive 0.917 12 2 1999 2016
Entrez Id: 100505887
Gene Symbol: LINC01672
LINC01672
long intergenic non-protein coding RNA 1672 268 0.462 0.846 0.010 None 1.000 1 0 1991 1991
Entrez Id: 4535
Gene Symbol: ND1
ND1
P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 260 0.522 0.769 0.130 None 1.000 8 8 2002 2014
Entrez Id: 103
Gene Symbol: ADAR
ADAR
P55265 adenosine deaminase RNA specific Enzyme 256 0.501 0.808 2.6E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4254
Gene Symbol: KITLG
KITLG
P21583 KIT ligand 249 0.473 0.885 0.85 0.010 None 1.000 1 0 2004 2004
Entrez Id: 2690
Gene Symbol: GHR
GHR
P10912 growth hormone receptor Signaling 247 0.490 0.846 8.4E-05 0.010 None 1.000 1 1 2018 2018
Entrez Id: 6389
Gene Symbol: SDHA
SDHA
P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 246 0.517 0.731 2.6E-10 0.730 moderate 0.917 12 3 1992 2017
Entrez Id: 1371
Gene Symbol: CPOX
CPOX
P36551 coproporphyrinogen oxidase Enzyme 246 0.488 0.846 0.17 0.050 None 1.000 5 0 1996 2019
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.010 None 1.000 1 0 2019 2019