Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.800 None 0.977 301 32 1991 2020
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.700 None 0.966 88 4 1998 2019
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2
P16885 phospholipase C gamma 2 Enzyme 82 0.588 0.808 1.00 0.700 None 0.929 14 2 2007 2020
Entrez Id: 25913
Gene Symbol: POT1
POT1
Q9NUX5 protection of telomeres 1 Nucleic acid binding 107 0.560 0.731 0.85 0.640 None 1.000 5 2 2013 2018
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21
A0A0B4J1V1 immunoglobulin heavy variable 3-21 11 0.780 0.192 0.600 None 0.947 19 0 2005 2018
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
Q99572 purinergic receptor P2X 7 Ion channel 337 0.450 0.808 3.3E-11 0.590 None 0.700 10 0 2000 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.500 None 0.974 267 4 1987 2020
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
O75533 splicing factor 3b subunit 1 Nucleic acid binding 200 0.511 0.731 1.00 0.500 None 0.974 38 5 2011 2019
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
Q15306 interferon regulatory factor 4 Transcription factor 203 0.491 0.769 0.86 0.500 None 0.933 15 3 2008 2019
Entrez Id: 51176
Gene Symbol: LEF1
LEF1
Q9UJU2 lymphoid enhancer binding factor 1 211 0.486 0.769 1.00 0.500 None 1.000 15 3 2005 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.470 None 0.900 10 8 2007 2019
Entrez Id: 7514
Gene Symbol: XPO1
XPO1
O14980 exportin 1 Receptor 178 0.504 0.692 1.00 0.440 None 1.000 5 2 2012 2019
Entrez Id: 11262
Gene Symbol: SP140
SP140
Q13342 SP140 nuclear body protein 32 0.691 0.577 5.0E-08 0.430 None 1.000 8 3 2008 2017
Entrez Id: 90427
Gene Symbol: BMF
BMF
Q96LC9 Bcl2 modifying factor 42 0.663 0.423 6.8E-03 0.420 None 1.000 4 2 2012 2017
Entrez Id: 55289
Gene Symbol: ACOXL
ACOXL
Q9NUZ1 acyl-CoA oxidase like Enzyme 46 0.674 0.577 5.2E-15 0.410 None 1.000 8 5 2008 2017
Entrez Id: 9855
Gene Symbol: FARP2
FARP2
O94887 FERM, ARH/RhoGEF and pleckstrin domain protein 2 38 0.678 0.615 4.6E-36 0.410 None 1.000 2 2 2010 2013
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
Q9BZL6 protein kinase D2 Kinase 40 0.666 0.538 1.00 0.410 None 1.000 1 1 2008 2008
Entrez Id: 695
Gene Symbol: BTK
BTK
Q06187 Bruton tyrosine kinase Kinase 290 0.464 0.808 1.00 0.400 None 0.982 114 2 2011 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.400 None 0.884 43 0 1988 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.400 None 1.000 41 0 2008 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 1.000 27 0 1983 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 22 0 1989 2019
Entrez Id: 3676
Gene Symbol: ITGA4
ITGA4
P13612 integrin subunit alpha 4 123 0.558 0.769 1.0E-04 0.400 None 0.952 21 0 2002 2019
Entrez Id: 330
Gene Symbol: BIRC3
BIRC3
Q13489 baculoviral IAP repeat containing 3 Enzyme modulator 209 0.491 0.769 6.6E-02 0.400 None 1.000 16 0 2004 2020
Entrez Id: 604
Gene Symbol: BCL6
BCL6
P41182 BCL6 transcription repressor 309 0.444 0.808 0.96 0.400 None 0.933 15 0 1996 2020