Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3394
Gene Symbol: IRF8
IRF8
Q02556 interferon regulatory factor 8 Transcription factor 149 0.539 0.808 0.95 0.100 None 1.000 15 0 1998 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.800 15 0 1989 2019
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related receptor tyrosine kinase 3 Kinase 270 0.462 0.654 0.61 0.100 None 0.929 14 0 1997 2017
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.100 None 1.000 14 0 2005 2019
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
P11413 glucose-6-phosphate dehydrogenase Enzyme 410 0.424 0.846 0.97 0.100 None 0.833 12 0 1977 1996
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
P31269 homeobox A9 147 0.521 0.692 4.4E-05 0.100 None 1.000 12 0 1999 2013
Entrez Id: 3562
Gene Symbol: IL3
IL3
P08700 interleukin 3 211 0.489 0.731 2.6E-09 0.100 None 1.000 12 0 1991 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 12 0 2003 2018
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
Q14289 protein tyrosine kinase 2 beta Kinase 319 0.448 0.808 0.94 0.100 None 1.000 11 0 1988 2018
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
P24158 proteinase 3 Enzyme 215 0.503 0.808 3.8E-05 0.400 None 1.000 11 0 1997 2011
Entrez Id: 5777
Gene Symbol: PTPN6
PTPN6
P29350 protein tyrosine phosphatase non-receptor type 6 218 0.485 0.769 1.00 0.100 None 0.909 11 0 2007 2018
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.100 None 1.000 11 0 2007 2018
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 446 0.422 0.808 1.00 0.400 None 1.000 11 0 1994 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.100 None 1.000 10 0 1994 2014
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 1.000 10 0 2012 2020
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.100 None 1.000 10 0 2004 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.100 None 1.000 10 0 1985 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 1.000 10 0 2010 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 375 0.430 0.808 0.96 0.100 None 1.000 10 0 2005 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 10 0 2007 2019
Entrez Id: 10018
Gene Symbol: BCL2L11
BCL2L11
O43521 BCL2 like 11 173 0.510 0.731 0.89 0.090 None 1.000 9 0 2007 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.090 None 1.000 9 0 2007 2018
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.090 None 0.889 9 0 1997 2005
Entrez Id: 5524
Gene Symbol: PTPA
PTPA
Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 245 0.480 0.846 0.99 0.090 None 1.000 9 0 2007 2019
Entrez Id: 6714
Gene Symbol: SRC
SRC
P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 265 0.467 0.885 1.00 0.090 None 1.000 9 0 2006 2017