Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.010 None 1.000 1 0 2015 2015
Entrez Id: 923
Gene Symbol: CD6
CD6
P30203 CD6 molecule Enzyme 216 0.489 0.808 9.3E-05 0.010 None 1.000 1 0 2020 2020
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4
O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 84 0.582 0.692 2.0E-06 0.010 None 1.000 1 0 2014 2014
Entrez Id: 9508
Gene Symbol: ADAMTS3
ADAMTS3
O15072 ADAM metallopeptidase with thrombospondin type 1 motif 3 Enzyme 116 0.581 0.808 1.0E-10 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.100 None 0 0
Entrez Id: 5832
Gene Symbol: ALDH18A1
ALDH18A1
P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 206 0.551 0.769 8.1E-04 0.100 None 0 1
Entrez Id: 10468
Gene Symbol: FST
FST
P19883 follistatin Enzyme modulator 182 0.513 0.731 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.010 None 1.000 1 0 2015 2015
Entrez Id: 176
Gene Symbol: ACAN
ACAN
P16112 aggrecan Extracellular structure 187 0.528 0.846 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.010 None 1.000 1 1 2017 2017
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 590 0.393 0.885 0.97 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2015 2015
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.010 None 1.000 1 0 2017 2017
Entrez Id: 23481
Gene Symbol: PES1
PES1
O00541 pescadillo ribosomal biogenesis factor 1 Nucleic acid binding 46 0.656 0.538 0.72 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
P42226 signal transducer and activator of transcription 6 Nucleic acid binding 281 0.475 0.808 0.99 0.100 None 0 0
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.080 None 1.000 8 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.050 None 1.000 5 0 2017 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.030 None 1.000 3 0 2019 2019
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.030 None 1.000 3 0 2018 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.020 None 1.000 2 0 2002 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.020 None 0.500 2 0 2017 2018
Entrez Id: 10371
Gene Symbol: SEMA3A
SEMA3A
Q14563 semaphorin 3A Signaling 202 0.500 0.808 0.98 0.010 None 1.000 1 0 2015 2015
Entrez Id: 23101
Gene Symbol: MCF2L2
MCF2L2
Q86YR7 MCF.2 cell line derived transforming sequence-like 2 Signaling 60 0.628 0.577 1.2E-24 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
P40189 interleukin 6 signal transducer Signaling 260 0.475 0.808 1.00 0.010 None 1.000 1 0 2018 2018