Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.978 179 0 1996 2020
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.500 None 0.990 101 30 1977 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.952 84 3 2000 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.967 60 1 2006 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.400 None 0.965 57 0 2000 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.600 None 0.979 48 4 2002 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.911 45 1 2006 2020
Entrez Id: 54738
Gene Symbol: FEV
FEV 		Q99581 FEV transcription factor, ETS family member Transcription factor 86 0.593 0.692 8.1E-03 0.100 None 0.933 45 2 2000 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.600 None 0.911 45 5 1994 2020
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		P07550 adrenoceptor beta 2 G-protein coupled receptor 387 0.442 0.923 0.53 0.100 None 1.000 36 5 1993 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.300 None 0.972 36 2 2008 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.941 34 1 2000 2020
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3 		P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 110 0.588 0.692 1.4E-07 0.200 None 0.970 33 19 2009 2019
Entrez Id: 10144
Gene Symbol: FAM13A
FAM13A 		O94988 family with sequence similarity 13 member A 64 0.653 0.462 1.9E-18 0.500 None 1.000 31 12 2010 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.933 30 0 1999 2019
Entrez Id: 4321
Gene Symbol: MMP12
MMP12 		P39900 matrix metallopeptidase 12 Enzyme 216 0.484 0.885 0.100 None 1.000 30 6 2002 2020
Entrez Id: 2006
Gene Symbol: ELN
ELN 		P15502 elastin 545 0.415 0.885 2.1E-14 0.400 None 1.000 28 1 2005 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.300 None 0.963 27 2 2004 2019
Entrez Id: 5141
Gene Symbol: PDE4A
PDE4A 		P27815 phosphodiesterase 4A 168 0.523 0.846 0.98 0.100 None 1.000 27 0 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.300 None 0.963 27 0 2003 2019
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.400 None 0.923 26 3 1997 2017
Entrez Id: 3596
Gene Symbol: IL13
IL13 		P35225 interleukin 13 587 0.386 0.846 1.4E-02 0.100 None 0.962 26 4 2000 2020
Entrez Id: 64399
Gene Symbol: HHIP
HHIP 		Q96QV1 hedgehog interacting protein 122 0.550 0.654 0.95 0.100 None 1.000 25 2 2009 2019
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD 		P35247 surfactant protein D Surfactant 194 0.500 0.846 7.5E-05 0.700 None 0.917 24 8 2001 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.200 None 1.000 23 4 2001 2019