Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 73 0.401 0.808 0.15 0.800 None 0.933 6 1 1996 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.700 None 0.963 3 0 1988 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 93 0.380 0.808 1.00 0.700 None 0.957 2 0 1996 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.700 None 0.983 2 2 1992 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.700 None 0.992 1 0 2005 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.700 None 0.950 0 0 1992 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 12 0.501 0.846 0.98 0.660 None 1.000 0 0 2005 2019
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 14 0.468 0.769 0.99 0.660 None 1.000 0 0 1998 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.640 None 1.000 0 0 2004 2011
Entrez Id: 843
Gene Symbol: CASP10
CASP10 		Q92851 caspase 10 Enzyme 23 0.528 0.692 4.6E-12 0.610 None 1.000 0 0 2002 2002
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.600 None 1.000 1 0 1998 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.500 None 0.907 3 0 2000 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.500 None 1.000 2 0 1987 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1 		Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 10 0.453 0.846 0.14 0.500 None 0.944 1 1 2011 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.500 None 0.833 0 0 2003 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.460 None 0.857 1 0 2000 2018
Entrez Id: 26137
Gene Symbol: ZBTB20
ZBTB20 		Q9HC78 zinc finger and BTB domain containing 20 8 0.566 0.731 0.97 0.430 None 1.000 1 1 2011 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.979 4 0 1998 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.400 None 0.938 4 0 1992 2019
Entrez Id: 1806
Gene Symbol: DPYD
DPYD 		Q12882 dihydropyrimidine dehydrogenase Enzyme 45 0.493 0.846 3.4E-22 0.400 None 1.000 3 0 2000 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.989 3 0 1986 2019
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		O14497 AT-rich interaction domain 1A 48 0.455 0.846 1.00 0.400 None 1.000 3 0 2011 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 1.000 2 0 1995 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.400 None 0.975 2 0 1991 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.912 2 0 1992 2019