Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 1.000 None 0.983 1637 35 1986 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.800 strong 0.950 535 32 1994 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.800 strong 0.950 101 4 1997 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.800 None 1.000 25 6 1984 2018
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.700 None 0.969 321 10 1987 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.700 None 0.943 209 13 1991 2020
Entrez Id: 4286
Gene Symbol: MITF
MITF 		O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.700 None 0.974 194 7 2002 2020
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.700 strong 0.961 128 3 1994 2020
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.700 strong 1.000 47 4 2001 2019
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.700 None 1.000 44 15 2003 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.700 strong 0.950 40 1 2010 2019
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		P50148 G protein subunit alpha q Enzyme modulator 219 0.516 0.808 0.98 0.700 None 0.967 30 2 1989 2019
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		P29992 G protein subunit alpha 11 Enzyme modulator 122 0.563 0.731 0.89 0.700 None 1.000 26 1 1989 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.700 None 1.000 15 4 1999 2018
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.700 None 0.917 12 6 2009 2018
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2 		P36507 mitogen-activated protein kinase kinase 2 Kinase 177 0.534 0.731 0.97 0.670 None 1.000 9 5 2011 2019
Entrez Id: 5879
Gene Symbol: RAC1
RAC1 		P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.600 None 1.000 19 2 2004 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.600 None 1.000 17 0 1993 2018
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C 		O00743 protein phosphatase 6 catalytic subunit 20 0.729 0.231 0.86 0.540 None 1.000 4 0 2012 2015
Entrez Id: 4157
Gene Symbol: MC1R
MC1R 		Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.500 None 0.959 194 15 1996 2020
Entrez Id: 7299
Gene Symbol: TYR
TYR 		P14679 tyrosinase Enzyme 281 0.473 0.808 5.0E-32 0.500 None 0.984 191 4 1988 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.500 None 0.967 183 23 1992 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.500 None 0.965 85 2 2005 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.500 None 0.976 84 3 2002 2020
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.500 None 1.000 77 5 2002 2019