Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1
Q6DJT9 PLAG1 zinc finger Transcription factor 219 0.493 0.808 1.00 0.100 None 0.974 39 0 1998 2020
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.100 None 0.952 21 0 1997 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.895 19 0 1992 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 10 0 1992 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.080 None 1.000 8 0 1998 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.060 None 1.000 6 0 2009 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.050 None 1.000 5 0 2000 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.040 None 1.000 4 0 2006 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.040 None 1.000 4 0 1998 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.030 None 1.000 3 0 2004 2018
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
P41212 ETS variant transcription factor 6 Transcription factor 241 0.477 0.731 0.97 0.030 None 1.000 3 0 2006 2018
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.030 None 1.000 3 0 2000 2009
Entrez Id: 4342
Gene Symbol: MOS
MOS
P00540 MOS proto-oncogene, serine/threonine kinase Kinase 78 0.617 0.500 0.59 0.030 None 1.000 3 0 1990 1997
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 0 2015 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.030 None 1.000 3 0 1989 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.030 None 1.000 3 0 2009 2016
Entrez Id: 7471
Gene Symbol: WNT1
WNT1
P04628 Wnt family member 1 Signaling 216 0.495 0.769 0.33 0.020 None 1.000 2 0 1992 2014
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor Kinase 623 0.378 0.885 1.00 0.020 None 1.000 2 0 2005 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.020 None 1.000 2 0 2004 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.020 None 1.000 2 0 2009 2015
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 644 0.372 0.846 0.71 0.020 None 1.000 2 0 2006 2019
Entrez Id: 23373
Gene Symbol: CRTC1
CRTC1
Q6UUV9 CREB regulated transcription coactivator 1 Transcription factor 115 0.565 0.692 0.53 0.020 None 1.000 2 0 2007 2013
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 2005 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.020 None 1.000 2 0 2009 2012
Entrez Id: 339896
Gene Symbol: GADL1
GADL1
Q6ZQY3 glutamate decarboxylase like 1 192 0.497 0.808 1.4E-21 0.020 None 1.000 2 0 2018 2019