Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0 0
Entrez Id: 7486
Gene Symbol: WRN
WRN
Q14191 WRN RecQ like helicase Enzyme 172 0.524 0.808 2.6E-34 0.100 None 0 0
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.550 None 0.875 8 0 1995 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.340 None 1.000 5 0 2003 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.520 None 1.000 4 0 2003 2010
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.030 None 1.000 3 0 2002 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.310 None 1.000 3 0 1997 2004
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.320 None 1.000 3 0 2004 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.030 None 1.000 3 0 2008 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2005 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.020 None 1.000 2 0 2005 2008
Entrez Id: 2810
Gene Symbol: SFN
SFN
P31947 stratifin Chaperone 105 0.561 0.769 0.37 0.310 None 1.000 2 0 2004 2007
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.020 None 1.000 2 0 2008 2008
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.210 None 1.000 2 0 2000 2007
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.020 None 1.000 2 0 2008 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.500 None 1.000 2 0 2009 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.310 None 1.000 2 0 2009 2019
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.020 None 1.000 2 0 2008 2008
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.110 None 1.000 1 0 2003 2003
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like Enzyme 110 0.551 0.654 4.4E-05 0.300 None 1.000 1 0 2016 2016
Entrez Id: 79977
Gene Symbol: GRHL2
GRHL2
Q6ISB3 grainyhead like transcription factor 2 Transcription factor 85 0.590 0.731 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 494324
Gene Symbol: MIR375
MIR375
microRNA 375 226 0.476 0.769 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5094
Gene Symbol: PCBP2
PCBP2
Q15366 poly(rC) binding protein 2 Enzyme 44 0.647 0.577 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase Enzyme 356 0.453 0.808 1.2E-15 0.010 None 1.000 1 0 2006 2006