Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.200 None 0.962 26 1 1993 2019
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.100 None 0.955 22 3 1998 2019
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.100 None 1.000 18 0 1995 2020
Entrez Id: 4038
Gene Symbol: LRP4
LRP4
O75096 LDL receptor related protein 4 151 0.568 0.692 1.4E-06 0.100 None 0.938 16 0 2011 2019
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
Q8IUH3 RNA binding motif protein 45 557 0.383 0.846 2.1E-10 0.100 None 0.938 16 0 1993 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 0.846 13 0 1996 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.100 None 1.000 12 0 1994 2018
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.200 None 1.000 12 1 2006 2015
Entrez Id: 7273
Gene Symbol: TTN
TTN
Q8WZ42 titin Kinase 366 0.470 0.885 2.6E-96 0.100 None 1.000 12 1 1993 2019
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
P04439 major histocompatibility complex, class I, A 672 0.370 0.846 1.3E-03 0.190 None 1.000 11 3 1978 2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 427 0.416 0.846 2.4E-02 0.200 None 0.909 11 1 1993 2015
Entrez Id: 590
Gene Symbol: BCHE
BCHE
P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.100 None 1.000 10 0 2011 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 10 0 1996 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.090 None 1.000 9 0 2013 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.090 None 1.000 9 0 2005 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.090 None 1.000 9 0 1996 2018
Entrez Id: 3669
Gene Symbol: ISG20
ISG20
Q96AZ6 interferon stimulated exonuclease gene 20 414 0.414 0.846 2.9E-03 0.090 None 1.000 9 0 2005 2017
Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
O43927 C-X-C motif chemokine ligand 13 Signaling 246 0.472 0.731 0.83 0.090 None 1.000 9 0 2006 2019
Entrez Id: 326
Gene Symbol: AIRE
AIRE
O43918 autoimmune regulator 175 0.516 0.808 4.0E-12 0.080 None 0.875 8 1 2008 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.080 None 1.000 8 0 1995 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.080 None 0.875 8 0 2009 2018
Entrez Id: 27335
Gene Symbol: EIF3K
EIF3K
Q9UBQ5 eukaryotic translation initiation factor 3 subunit K 42 0.650 0.577 2.1E-03 0.080 None 0.875 8 0 2016 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.080 None 0.750 8 0 1994 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.360 None 1.000 8 0 1983 2018
Entrez Id: 1134
Gene Symbol: CHRNA1
CHRNA1
P02708 cholinergic receptor nicotinic alpha 1 subunit Ion channel 109 0.615 0.577 2.1E-08 0.070 None 0.857 7 1 1991 2017