Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 0.996 249 0 2001 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 0.987 236 0 2004 2020
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.400 None 0.989 190 0 1996 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 0.954 173 0 2011 2020
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 Calcium-binding protein 308 0.448 0.769 6.2E-03 0.400 None 0.962 160 0 1992 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.600 None 0.968 154 0 1998 2020
Entrez Id: 3732
Gene Symbol: CD82
CD82
P27701 CD82 molecule 172 0.507 0.731 1.3E-08 0.600 None 0.973 150 0 1995 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.400 None 0.980 149 0 2004 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.939 148 0 1989 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.400 None 0.972 144 0 1999 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.986 141 0 1994 2020
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 644 0.372 0.846 0.71 0.400 None 0.986 141 0 1997 2020
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.400 None 0.986 140 0 1993 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 0.976 126 0 2007 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 0.984 125 0 2017 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.100 None 1.000 125 0 1996 2019
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
Q04609 folate hydrolase 1 Enzyme 311 0.453 0.885 6.2E-09 0.100 None 0.983 115 0 1997 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.400 None 0.991 115 0 2003 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 0.925 106 0 1995 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.400 None 0.990 103 0 1989 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.400 None 0.981 103 0 1990 2019
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
P49767 vascular endothelial growth factor C Signaling 291 0.459 0.769 0.50 0.100 None 0.970 101 0 1997 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.980 100 0 1990 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.400 None 0.960 100 0 1993 2020
Entrez Id: 9112
Gene Symbol: MTA1
MTA1
Q13330 metastasis associated 1 Nucleic acid binding 118 0.547 0.692 1.00 0.100 None 0.949 98 0 1994 2019