Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.400 None 0.976 165 1 1997 2020
Entrez Id: 6275
Gene Symbol: S100A4
S100A4 		P26447 S100 calcium binding protein A4 Calcium-binding protein 308 0.448 0.769 6.2E-03 0.400 None 0.962 160 0 1992 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.600 None 0.968 154 0 1998 2020
Entrez Id: 3732
Gene Symbol: CD82
CD82 		P27701 CD82 molecule 172 0.507 0.731 1.3E-08 0.600 None 0.973 150 0 1995 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.400 None 0.980 149 0 2004 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.939 148 0 1989 2020
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.100 None 0.986 145 5 1997 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE 		Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.400 None 0.972 144 0 1999 2020
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1 		metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.400 None 0.993 142 1 2003 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.400 None 0.972 142 3 1995 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.986 141 0 1994 2020
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 644 0.372 0.846 0.71 0.400 None 0.986 141 0 1997 2020
Entrez Id: 3082
Gene Symbol: HGF
HGF 		P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.400 None 0.986 140 0 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 0.942 139 2 1992 2020
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1 		P37275 zinc finger E-box binding homeobox 1 Transcription factor 310 0.442 0.808 0.97 0.100 None 0.978 135 2 2006 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.978 134 1 1992 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 726 0.363 0.846 0.100 None 0.976 126 0 2007 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 0.984 125 0 2017 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.100 None 1.000 125 0 1996 2019
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		Q04609 folate hydrolase 1 Enzyme 311 0.453 0.885 6.2E-09 0.100 None 0.983 115 0 1997 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.400 None 0.991 115 0 2003 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 0.982 109 1 2005 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 0.925 106 0 1995 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.400 None 0.990 103 0 1989 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.400 None 0.981 103 0 1990 2019