Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.947 38 0 2008 2019
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.400 None 1.000 18 1 1997 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.400 None 1.000 13 0 2013 2020
Entrez Id: 2915
Gene Symbol: GRM5
GRM5
P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 189 0.525 0.846 1.00 0.400 None 1.000 12 0 2010 2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.380 None 0.889 9 0 2008 2020
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.350 None 1.000 6 0 2007 2019
Entrez Id: 6335
Gene Symbol: SCN9A
SCN9A
Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 213 0.543 0.615 4.8E-19 0.350 None 1.000 6 1 2007 2018
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.340 None 1.000 5 0 2008 2019
Entrez Id: 51083
Gene Symbol: GAL
GAL
P22466 galanin and GMAP prepropeptide 226 0.493 0.846 4.4E-06 0.320 None 1.000 3 0 2008 2019
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 140 0.555 0.692 3.7E-02 0.320 None 1.000 3 0 2011 2020
Entrez Id: 6336
Gene Symbol: SCN10A
SCN10A
Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 147 0.566 0.692 9.9E-38 0.320 None 1.000 3 0 2008 2020
Entrez Id: 5592
Gene Symbol: PRKG1
PRKG1
Q13976 protein kinase cGMP-dependent 1 Kinase 114 0.603 0.769 1.00 0.310 None 1.000 2 0 2017 2018
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
P04629 neurotrophic receptor tyrosine kinase 1 Kinase 443 0.422 0.808 2.0E-06 0.310 None 1.000 2 0 2008 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.300 None 1.000 19 0 2004 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.300 None 1.000 13 0 2005 2019
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1
P54289 calcium voltage-gated channel auxiliary subunit alpha2delta 1 Ion channel 82 0.641 0.500 1.00 0.300 None 1.000 4 0 2007 2013
Entrez Id: 2674
Gene Symbol: GFRA1
GFRA1
P56159 GDNF family receptor alpha 1 73 0.619 0.615 0.12 0.300 None 1.000 1 0 2008 2008
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.300 None 1.000 1 0 2014 2014
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 153 0.533 0.731 1.7E-03 0.240 None 1.000 5 0 2010 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.220 None 1.000 4 1 2011 2017
Entrez Id: 156
Gene Symbol: GRK2
GRK2
P25098 G protein-coupled receptor kinase 2 Kinase 159 0.532 0.654 1.00 0.210 None 1.000 2 0 2014 2019
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
P11215 integrin subunit alpha M 343 0.443 0.808 3.3E-11 0.210 None 1.000 2 0 2004 2018
Entrez Id: 1520
Gene Symbol: CTSS
CTSS
P25774 cathepsin S Enzyme 131 0.539 0.731 0.34 0.200 None 1.000 2 0 2007 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.200 None 1.000 1 0 2014 2014
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
Q9UBR2 cathepsin Z Enzyme 51 0.647 0.577 2.3E-16 0.200 None 1.000 1 0 2008 2008