Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.010 None 1.000 1 0 2003 2003
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
P51608 methyl-CpG binding protein 2 Epigenetic regulator 664 0.414 0.846 0.89 0.010 None 1.000 1 0 2018 2018
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.010 None 1.000 1 0 2008 2008
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.010 None 1.000 1 0 1999 1999
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.010 None 1.000 1 0 2014 2014
Entrez Id: 2896
Gene Symbol: GRN
GRN
P28799 granulin precursor 412 0.435 0.846 7.0E-02 0.100 None 1.000 25 1 2012 2019
Entrez Id: 3956
Gene Symbol: LGALS1
LGALS1
P09382 galectin 1 Signaling 362 0.435 0.846 4.5E-03 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.010 None 1.000 1 0 2012 2012
Entrez Id: 1509
Gene Symbol: CTSD
CTSD
P07339 cathepsin D Enzyme 242 0.478 0.846 9.2E-04 0.300 None 1.000 21 1 1995 2020
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
Q99259 glutamate decarboxylase 1 Enzyme 245 0.486 0.885 4.6E-02 0.010 None 1.000 1 0 2004 2004
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.030 None 1.000 3 0 2014 2017
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
P98161 polycystin 1, transient receptor potential channel interacting 217 0.493 0.769 1.00 0.010 None 1.000 1 0 2000 2000
Entrez Id: 4691
Gene Symbol: NCL
NCL
P19338 nucleolin Nucleic acid binding 167 0.509 0.808 1.00 0.090 None 0.889 9 0 1999 2019
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1
Q12791 potassium calcium-activated channel subfamily M alpha 1 Ion channel 205 0.518 0.846 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 7942
Gene Symbol: TFEB
TFEB
P19484 transcription factor EB 150 0.527 0.731 0.90 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2572
Gene Symbol: GAD2
GAD2
Q05329 glutamate decarboxylase 2 Enzyme 173 0.529 0.731 0.75 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5660
Gene Symbol: PSAP
PSAP
P07602 prosaposin 189 0.532 0.846 0.99 0.020 None 1.000 2 0 2014 2017
Entrez Id: 4142
Gene Symbol: MAS1
MAS1
P04201 MAS1 proto-oncogene, G protein-coupled receptor G-protein coupled receptor 142 0.533 0.769 8.3E-05 0.010 None 1.000 1 0 2004 2004
Entrez Id: 1200
Gene Symbol: TPP1
TPP1
O14773 tripeptidyl peptidase 1 Enzyme 151 0.551 0.808 6.3E-07 0.700 None 0.968 63 23 1991 2019
Entrez Id: 825
Gene Symbol: CAPN3
CAPN3
P20807 calpain 3 Enzyme 137 0.564 0.615 3.6E-19 0.020 None 1.000 2 0 2018 2018
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 160 0.566 0.577 9.0E-09 0.400 None 1.000 13 0 2011 2019
Entrez Id: 1201
Gene Symbol: CLN3
CLN3
Q13286 CLN3 lysosomal/endosomal transmembrane protein, battenin Transporter 120 0.572 0.692 1.3E-07 0.700 None 0.957 69 14 1993 2019
Entrez Id: 800
Gene Symbol: CALD1
CALD1
Q05682 caldesmon 1 94 0.578 0.692 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 10404
Gene Symbol: CPQ
CPQ
Q9Y646 carboxypeptidase Q Enzyme 87 0.579 0.769 1.3E-14 0.010 None 1.000 1 0 2001 2001