Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1806
Gene Symbol: DPYD
DPYD 		Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.370 None 1.000 8 6 2000 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.400 None 0.938 16 4 2006 2019
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		Q92887 ATP binding cassette subfamily C member 2 Transporter 254 0.483 0.808 5.2E-47 0.050 None 1.000 5 4 2008 2016
Entrez Id: 2542
Gene Symbol: SLC37A4
SLC37A4 		O43826 solute carrier family 37 member 4 Transporter 73 0.617 0.654 1.7E-05 0.170 None 0.857 7 3 2004 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 1.000 3 3 2010 2014
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		P33527 ATP binding cassette subfamily C member 1 Transporter 333 0.445 0.808 1.2E-03 0.020 None 1.000 2 3 2013 2018
Entrez Id: 115072896
Gene Symbol: SLCO1B3-SLCO1B7
SLCO1B3-SLCO1B7 		SLCO1B3-SLCO1B7 readthrough 8 0.839 0.077 0.010 None 1.000 1 3 2019 2019
Entrez Id: 978
Gene Symbol: CDA
CDA 		P32320 cytidine deaminase Enzyme 103 0.558 0.731 8.1E-03 0.080 None 0.875 8 2 2008 2019
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6 		P19224 UDP glucuronosyltransferase family 1 member A6 115 0.560 0.654 3.0E-07 0.060 None 1.000 6 2 2004 2017
Entrez Id: 54657
Gene Symbol: UGT1A4
UGT1A4 		P22310 UDP glucuronosyltransferase family 1 member A4 84 0.595 0.654 6.0E-07 0.050 None 1.000 5 2 2004 2016
Entrez Id: 54575
Gene Symbol: UGT1A10
UGT1A10 		Q9HAW8 UDP glucuronosyltransferase family 1 member A10 88 0.588 0.615 4.6E-19 0.050 None 1.000 5 2 2004 2016
Entrez Id: 54576
Gene Symbol: UGT1A8
UGT1A8 		Q9HAW9 UDP glucuronosyltransferase family 1 member A8 90 0.588 0.654 1.3E-09 0.050 None 1.000 5 2 2004 2016
Entrez Id: 54577
Gene Symbol: UGT1A7
UGT1A7 		Q9HAW7 UDP glucuronosyltransferase family 1 member A7 125 0.550 0.692 8.7E-14 0.050 None 1.000 5 2 2004 2016
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.030 None 1.000 3 2 2006 2019
Entrez Id: 54600
Gene Symbol: UGT1A9
UGT1A9 		O60656 UDP glucuronosyltransferase family 1 member A9 94 0.590 0.577 5.4E-08 0.020 None 1.000 2 2 2015 2015
Entrez Id: 54659
Gene Symbol: UGT1A3
UGT1A3 		P35503 UDP glucuronosyltransferase family 1 member A3 66 0.623 0.538 1.3E-09 0.020 None 1.000 2 2 2015 2015
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.020 None 1.000 2 2 2012 2014
Entrez Id: 2030
Gene Symbol: SLC29A1
SLC29A1 		Q99808 solute carrier family 29 member 1 (Augustine blood group) Transporter 91 0.587 0.731 0.90 0.020 None 1.000 2 2 2015 2015
Entrez Id: 28234
Gene Symbol: SLCO1B3
SLCO1B3 		Q9NPD5 solute carrier organic anion transporter family member 1B3 Transporter 87 0.592 0.769 5.3E-24 0.020 None 0.500 2 2 2008 2013
Entrez Id: 54579
Gene Symbol: UGT1A5
UGT1A5 		P35504 UDP glucuronosyltransferase family 1 member A5 53 0.656 0.462 9.4E-09 0.020 None 1.000 2 2 2015 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 2 2015 2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 2 2011 2011
Entrez Id: 1635
Gene Symbol: DCTD
DCTD 		P32321 dCMP deaminase Enzyme 10 0.780 0.192 7.1E-04 0.010 None 1.000 1 2 2015 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 2 2018 2018
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1 		P22309 UDP glucuronosyltransferase family 1 member A1 302 0.464 0.769 3.3E-06 0.400 None 0.907 75 1 2004 2020