Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
P32245 melanocortin 4 receptor G-protein coupled receptor 149 0.535 0.692 9.2E-04 1.000 None 0.961 283 53 1997 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 1.000 None 0.960 174 9 1997 2020
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.900 strong 0.959 97 11 1996 2020
Entrez Id: 1363
Gene Symbol: CPE
CPE
P16870 carboxypeptidase E 101 0.584 0.692 0.99 0.730 moderate 0.923 13 0 1991 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.700 None 0.952 794 7 1973 2020
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.700 None 0.930 214 13 1966 2019
Entrez Id: 7352
Gene Symbol: UCP3
UCP3
P55916 uncoupling protein 3 Transporter 66 0.619 0.577 9.6E-10 0.700 None 0.907 43 9 1998 2018
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 140 0.548 0.615 2.7E-09 0.700 None 0.857 42 6 1997 2018
Entrez Id: 25970
Gene Symbol: SH2B1
SH2B1
Q9NRF2 SH2B adaptor protein 1 140 0.566 0.731 0.97 0.700 moderate 0.906 32 5 2009 2020
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 247 0.498 0.808 5.0E-08 0.700 moderate 0.786 28 5 2001 2019
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 Transcription factor 84 0.626 0.654 1.00 0.700 strong 0.955 22 4 1998 2019
Entrez Id: 181
Gene Symbol: AGRP
AGRP
O00253 agouti related neuropeptide Signaling 233 0.488 0.769 7.0E-04 0.700 None 0.938 16 2 1997 2019
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2
Q15466 nuclear receptor subfamily 0 group B member 2 Nuclear receptor 251 0.474 0.808 8.3E-06 0.690 limited 1.000 9 2 2001 2020
Entrez Id: 585
Gene Symbol: BBS4
BBS4
Q96RK4 Bardet-Biedl syndrome 4 63 0.647 0.615 1.5E-16 0.660 strong 1.000 7 1 2001 2019
Entrez Id: 8195
Gene Symbol: MKKS
MKKS
Q9NPJ1 McKusick-Kaufman syndrome 123 0.566 0.692 2.1E-09 0.660 strong 0.833 6 3 2000 2013
Entrez Id: 582
Gene Symbol: BBS1
BBS1
Q8NFJ9 Bardet-Biedl syndrome 1 111 0.593 0.692 3.4E-12 0.620 strong 1.000 3 0 2002 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.600 None 0.933 374 14 1998 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.600 None 0.970 134 6 2001 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.600 None 0.980 101 2 2001 2020
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.600 None 0.982 55 6 2005 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.600 None 1.000 49 3 2008 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.600 None 0.979 48 2 2001 2020
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.600 None 0.949 39 4 1995 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.600 None 1.000 39 0 2005 2020
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
P28845 hydroxysteroid 11-beta dehydrogenase 1 163 0.520 0.731 0.42 0.600 None 0.970 33 5 2002 2019