Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 1.000 None 0.953 214 23 1987 2020
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.740 None 1.000 4 10 2002 2019
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.700 None 1.000 19 2 1987 2017
Entrez Id: 9401
Gene Symbol: RECQL4
RECQL4
O94761 RecQ like helicase 4 Enzyme 249 0.496 0.808 3.3E-35 0.500 strong 0.833 12 0 2003 2018
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.450 None 0.857 7 1 2002 2018
Entrez Id: 2914
Gene Symbol: GRM4
GRM4
Q14833 glutamate metabotropic receptor 4 G-protein coupled receptor 54 0.636 0.500 0.99 0.450 None 1.000 6 1 2013 2020
Entrez Id: 7486
Gene Symbol: WRN
WRN
Q14191 WRN RecQ like helicase Enzyme 172 0.524 0.808 2.6E-34 0.410 None 1.000 1 0 2006 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 1.000 69 2 1996 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.400 None 1.000 45 0 2005 2020
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.400 None 1.000 44 0 2000 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 0.976 42 0 1997 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.400 None 1.000 22 1 1999 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.400 None 1.000 17 0 2004 2020
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.400 None 1.000 15 0 1991 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 1.000 12 0 1993 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.390 None 0.900 10 1 2006 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.390 None 1.000 9 0 2016 2019
Entrez Id: 1719
Gene Symbol: DHFR
DHFR
P00374 dihydrofolate reductase Enzyme 191 0.513 0.808 3.4E-02 0.380 None 1.000 8 0 2003 2017
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.380 None 1.000 8 0 2010 2018
Entrez Id: 7262
Gene Symbol: PHLDA2
PHLDA2
Q53GA4 pleckstrin homology like domain family A member 2 58 0.636 0.615 0.15 0.380 None 1.000 8 0 2012 2019
Entrez Id: 3756
Gene Symbol: KCNH1
KCNH1
O95259 potassium voltage-gated channel subfamily H member 1 Ion channel 180 0.542 0.731 0.55 0.360 None 1.000 6 0 2012 2015
Entrez Id: 8792
Gene Symbol: TNFRSF11A
TNFRSF11A
Q9Y6Q6 TNF receptor superfamily member 11a 270 0.480 0.846 8.8E-03 0.360 limited 1.000 6 0 2001 2018
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 344 0.442 0.885 6.0E-02 0.350 None 1.000 6 0 1994 2018
Entrez Id: 406920
Gene Symbol: MIR130B
MIR130B
microRNA 130b 115 0.547 0.808 0.350 None 1.000 6 0 2012 2019
Entrez Id: 407050
Gene Symbol: MIR93
MIR93
microRNA 93 171 0.507 0.808 0.350 None 1.000 6 0 2012 2019