Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.060 None 1.000 6 0 2005 2016
Entrez Id: 2152
Gene Symbol: F3
F3
P13726 coagulation factor III, tissue factor Receptor 456 0.415 0.846 1.9E-02 0.060 None 1.000 6 0 2006 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.340 None 1.000 5 0 1999 2009
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.050 None 1.000 5 0 2011 2017
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.050 None 1.000 5 1 2011 2014
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.050 None 1.000 5 0 1992 2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.440 None 1.000 5 0 2002 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.350 None 1.000 5 0 2002 2019
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.050 None 1.000 5 0 2011 2014
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.050 None 1.000 5 0 2002 2017
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.050 None 1.000 5 0 2004 2015
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.330 None 1.000 5 0 2007 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.330 None 1.000 5 0 2000 2008
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
P05556 integrin subunit beta 1 Receptor 210 0.496 0.808 0.98 0.050 None 1.000 5 0 2003 2007
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.050 None 1.000 5 0 2005 2011
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 536 0.420 0.885 0.68 0.050 None 0.800 5 0 2013 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.050 None 1.000 5 0 2017 2020
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin Extracellular structure 146 0.525 0.692 5.9E-25 0.340 None 1.000 5 0 2001 2018
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.050 None 1.000 5 0 2005 2018
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.040 None 1.000 4 0 2004 2006
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.040 None 1.000 4 0 2003 2017
Entrez Id: 6286
Gene Symbol: S100P
S100P
P25815 S100 calcium binding protein P Calcium-binding protein 11 0.780 0.346 3.3E-02 0.040 None 1.000 4 0 2004 2007
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
O14786 neuropilin 1 246 0.476 0.808 0.99 0.340 None 1.000 4 0 2004 2018
Entrez Id: 415116
Gene Symbol: PIM3
PIM3
Q86V86 Pim-3 proto-oncogene, serine/threonine kinase 62 0.621 0.654 0.98 0.040 None 1.000 4 0 2009 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.040 None 1.000 4 0 2011 2012