Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.500 None 0.989 264 15 2004 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.500 None 0.972 142 40 1999 2019
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.600 None 0.979 141 3 1989 2020
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B 152 0.533 0.808 1.00 0.600 None 0.991 110 1 1993 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.200 None 0.922 90 1 1994 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.400 None 0.879 58 0 1992 2019
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 160 0.566 0.577 9.0E-09 0.600 strong 0.946 56 4 2007 2019
Entrez Id: 79594
Gene Symbol: MUL1
MUL1
Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.100 None 1.000 56 2 2002 2019
Entrez Id: 4036
Gene Symbol: LRP2
LRP2
P98164 LDL receptor related protein 2 254 0.491 0.846 1.00 0.100 None 0.979 47 0 2010 2019
Entrez Id: 9627
Gene Symbol: SNCAIP
SNCAIP
Q9Y6H5 synuclein alpha interacting protein 44 0.691 0.423 3.3E-04 0.100 None 1.000 42 4 2000 2019
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
O43464 HtrA serine peptidase 2 151 0.542 0.692 3.6E-03 0.100 None 0.969 32 4 2005 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.300 None 0.875 32 2 2002 2020
Entrez Id: 1644
Gene Symbol: DDC
DDC
P20711 dopa decarboxylase 164 0.535 0.769 3.8E-08 0.600 None 1.000 28 0 1988 2019
Entrez Id: 5309
Gene Symbol: PITX3
PITX3
O75364 paired like homeodomain 3 93 0.585 0.692 0.81 0.300 None 0.893 28 4 2001 2020
Entrez Id: 100359403
Gene Symbol: PARK16
PARK16
Parkinson disease 16 (susceptibility) 5 0.861 0.077 0.400 None 0.963 27 0 2009 2019
Entrez Id: 10200
Gene Symbol: MPHOSPH6
MPHOSPH6
Q99547 M-phase phosphoprotein 6 24 0.729 0.308 4.1E-04 0.100 None 1.000 26 1 2000 2019
Entrez Id: 2630
Gene Symbol: GBAP1
GBAP1
glucosylceramidase beta pseudogene 1 64 0.623 0.538 0.100 None 1.000 26 1 2005 2019
Entrez Id: 4359
Gene Symbol: MPZ
MPZ
P25189 myelin protein zero 249 0.503 0.846 0.27 0.100 None 1.000 26 0 2000 2019
Entrez Id: 26058
Gene Symbol: GIGYF2
GIGYF2
Q6Y7W6 GRB10 interacting GYF protein 2 54 0.711 0.269 1.00 0.100 None 0.800 25 9 2005 2017
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1
Q8IXJ9 ASXL transcriptional regulator 1 296 0.482 0.808 1.3E-14 0.100 None 0.957 23 0 2017 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 23 1 2001 2019
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
P21397 monoamine oxidase A 300 0.465 0.769 1.00 0.400 None 0.870 23 2 1994 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 219 0.504 0.769 1.00 0.100 None 0.957 23 0 2017 2020
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.100 None 0.957 23 0 2017 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 22 2 2017 2020