Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1644
Gene Symbol: DDC
DDC 		P20711 dopa decarboxylase 30 0.535 0.769 3.8E-08 0.600 None 1.000 2 0 1988 2019
Entrez Id: 7054
Gene Symbol: TH
TH 		P07101 tyrosine hydroxylase 51 0.462 0.885 1.7E-06 0.600 None 0.979 1 0 1989 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 93 0.437 0.885 1.1E-25 0.400 None 0.879 2 0 1992 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 147 0.379 0.962 0.18 0.400 None 0.971 3 0 1993 2020
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		P39905 glial cell derived neurotrophic factor Signaling 85 0.434 0.885 0.20 0.400 None 0.983 2 0 1993 2020
Entrez Id: 4129
Gene Symbol: MAOB
MAOB 		P27338 monoamine oxidase B 35 0.533 0.808 1.00 0.600 None 0.991 1 0 1993 2020
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3 		Q01959 solute carrier family 6 member 3 Transporter 58 0.453 0.885 1.00 0.400 None 0.935 4 0 1994 2020
Entrez Id: 4128
Gene Symbol: MAOA
MAOA 		P21397 monoamine oxidase A 48 0.465 0.769 1.00 0.400 None 0.870 1 0 1994 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 133 0.436 0.846 0.75 0.600 None 0.931 1 0 1995 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.400 None 0.906 1 0 1995 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR 		P06213 insulin receptor Kinase 60 0.432 0.846 3.6E-05 0.310 None 1.000 1 0 1996 2009
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		P21728 dopamine receptor D1 G-protein coupled receptor 52 0.529 0.808 0.96 0.570 None 1.000 1 0 1996 2020
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2 		Q05940 solute carrier family 18 member A2 Transporter 21 0.554 0.769 7.6E-02 0.600 None 0.966 1 0 1996 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 36 0.427 0.885 0.88 0.700 None 0.983 29 34 1997 2020
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 1.000 3 0 1997 2019
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		P29475 nitric oxide synthase 1 89 0.408 0.885 1.00 0.400 None 0.727 1 0 1997 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 137 0.381 0.923 9.7E-03 0.400 None 0.905 1 0 1997 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 42 0.431 0.846 6.9E-07 0.600 None 0.974 13 0 1998 2020
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		P05181 cytochrome P450 family 2 subfamily E member 1 61 0.459 0.885 8.1E-09 0.370 None 0.875 1 0 1998 2013
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 66 0.446 0.923 6.0E-03 0.500 None 0.972 2 24 1999 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.980 1 0 1999 2020
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.400 None 0.750 1 0 1999 2019
Entrez Id: 2208
Gene Symbol: FCER2
FCER2 		P06734 Fc fragment of IgE receptor II Receptor 6 0.560 0.654 7.6E-12 0.310 None 1.000 1 0 1999 2015
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 39 0.421 0.885 1.5E-06 0.400 None 1.000 1 0 1999 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 1.000 1 0 2001 2019