Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.400 None 1.000 1 0 2004 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		Q9UBK2 PPARG coactivator 1 alpha Transcription factor 18 0.453 0.885 1.00 0.400 None 0.857 1 0 2009 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 137 0.381 0.923 9.7E-03 0.400 None 0.905 1 0 1997 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.980 1 0 1999 2020
Entrez Id: 3313
Gene Symbol: HSPA9
HSPA9 		P38646 heat shock protein family A (Hsp70) member 9 21 0.502 0.885 0.97 0.400 None 0.818 1 0 2006 2018
Entrez Id: 10059
Gene Symbol: DNM1L
DNM1L 		O00429 dynamin 1 like Enzyme modulator 12 0.475 0.808 5.7E-04 0.400 None 1.000 1 0 2010 2020
Entrez Id: 4128
Gene Symbol: MAOA
MAOA 		P21397 monoamine oxidase A 48 0.465 0.769 1.00 0.400 None 0.870 1 0 1994 2019
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 26 0.436 0.846 2.6E-08 0.400 None 0.727 1 0 2002 2018
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		P29475 nitric oxide synthase 1 89 0.408 0.885 1.00 0.400 None 0.727 1 0 1997 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.400 None 0.906 1 0 1995 2020
Entrez Id: 55737
Gene Symbol: VPS35
VPS35 		Q96QK1 VPS35 retromer complex component Transporter 3 0.656 0.500 0.97 0.400 None 0.931 1 0 2011 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 39 0.421 0.885 1.5E-06 0.400 None 1.000 1 0 1999 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 84 0.344 0.885 1.3E-05 0.400 None 0.900 1 0 2002 2018
Entrez Id: 29058
Gene Symbol: TMEM230
TMEM230 		Q96A57 transmembrane protein 230 2 0.769 0.115 1.8E-04 0.400 None 0.923 1 0 2016 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.400 None 0.750 1 0 1999 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 1.000 1 0 2001 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 103 0.383 0.923 1.4E-02 0.380 None 0.778 2 0 2003 2019
Entrez Id: 54541
Gene Symbol: DDIT4
DDIT4 		Q9NX09 DNA damage inducible transcript 4 7 0.576 0.769 6.8E-04 0.380 None 1.000 1 0 2006 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		P05181 cytochrome P450 family 2 subfamily E member 1 61 0.459 0.885 8.1E-09 0.370 None 0.875 1 0 1998 2013
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 115 0.391 0.885 0.82 0.360 None 1.000 1 0 2009 2018
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		Q99683 mitogen-activated protein kinase kinase kinase 5 Kinase 15 0.513 0.808 0.52 0.360 None 0.833 1 0 2006 2020
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		P55008 allograft inflammatory factor 1 Calcium-binding protein 13 0.521 0.808 1.9E-06 0.340 None 1.000 1 0 2009 2019
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		P15559 NAD(P)H quinone dehydrogenase 1 52 0.434 0.885 1.2E-09 0.340 None 1.000 1 0 2001 2019
Entrez Id: 2941
Gene Symbol: GSTA4
GSTA4 		O15217 glutathione S-transferase alpha 4 10 0.678 0.462 1.1E-02 0.330 None 1.000 1 0 2005 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		P01344 insulin like growth factor 2 59 0.390 0.885 4.4E-02 0.330 None 1.000 1 0 2008 2017