Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 1 2000 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.030 None 1.000 3 0 1999 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.060 None 1.000 6 0 2000 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.070 None 1.000 7 0 1998 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.050 None 1.000 5 0 2002 2004
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2013 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.020 None 1.000 2 0 2005 2010
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.030 None 1.000 3 0 1999 2015
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.030 None 1.000 3 0 2003 2003
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.010 None 1.000 1 0 2013 2013
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12 		MT-CO2 pseudogene 12 703 0.368 0.962 0.030 None 1.000 3 0 2003 2003
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.010 None 1.000 1 0 1999 1999
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.020 None 1.000 2 0 2001 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 1999 2013
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.020 None 1.000 2 0 2001 2001
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 597 0.401 0.846 1.00 0.020 None 1.000 2 0 2010 2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.050 None 1.000 5 0 2001 2018
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1 		P07900 heat shock protein 90 alpha family class A member 1 Chaperone 455 0.411 0.923 0.86 0.010 None 1.000 1 0 2003 2003
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2 		O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.010 None 1.000 1 0 2007 2007
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 536 0.420 0.885 0.68 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 353
Gene Symbol: APRT
APRT 		P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6 		P20813 cytochrome P450 family 2 subfamily B member 6 388 0.428 0.846 1.9E-10 0.020 None 1.000 2 0 1993 1994